中华实验和临床病毒学杂志
中華實驗和臨床病毒學雜誌
중화실험화림상병독학잡지
CHINESE JOURNAL OF EXPERIMENTAL AND CLINICAL VIROLOGY
2011年
5期
371-373
,共3页
轮状病毒属%婴儿%新生%儿童%保健服务%肠炎%多器官功能衰竭
輪狀病毒屬%嬰兒%新生%兒童%保健服務%腸炎%多器官功能衰竭
륜상병독속%영인%신생%인동%보건복무%장염%다기관공능쇠갈
Rotavirus%Infant,newborn%Child health services%Enteritis%Multiple organ failure
目的 探讨小儿腹泻轮状病毒(RV)感染的发生率、影响因素和临床特征.方法 对我院2006年6月至2010年10月临床诊断为小儿腹泻病的住院患儿634例行胶体金免疫层析双抗体夹心法直接检测轮状病毒抗原,对确诊病例从发病年龄、发病季节、临床特点及多器官损害等方面进行总结分析.结果 634例标本中阳性308例,阳性率48.6％,6～12月龄阳性197例占66.3％,全年均可检出轮状病毒,第一季度63.8％、第四季度62.6％,阳性率较高,68.6％伴有心肌损害,41.2％伴有下呼吸道感染,13.3％伴有肝功损害,14.9％伴有肾脏损害,9.4％伴有惊厥,4.9％伴有血液系统损害.结论 轮状病毒是引起小儿腹泻的主要病原,6～12月龄的婴幼儿感染率最高,第一、第四季度是高发季节.轮状病毒感染可引起多器官功能损害.
目的 探討小兒腹瀉輪狀病毒(RV)感染的髮生率、影響因素和臨床特徵.方法 對我院2006年6月至2010年10月臨床診斷為小兒腹瀉病的住院患兒634例行膠體金免疫層析雙抗體夾心法直接檢測輪狀病毒抗原,對確診病例從髮病年齡、髮病季節、臨床特點及多器官損害等方麵進行總結分析.結果 634例標本中暘性308例,暘性率48.6％,6～12月齡暘性197例佔66.3％,全年均可檢齣輪狀病毒,第一季度63.8％、第四季度62.6％,暘性率較高,68.6％伴有心肌損害,41.2％伴有下呼吸道感染,13.3％伴有肝功損害,14.9％伴有腎髒損害,9.4％伴有驚厥,4.9％伴有血液繫統損害.結論 輪狀病毒是引起小兒腹瀉的主要病原,6～12月齡的嬰幼兒感染率最高,第一、第四季度是高髮季節.輪狀病毒感染可引起多器官功能損害.
목적 탐토소인복사륜상병독(RV)감염적발생솔、영향인소화림상특정.방법 대아원2006년6월지2010년10월림상진단위소인복사병적주원환인634례행효체금면역층석쌍항체협심법직접검측륜상병독항원,대학진병례종발병년령、발병계절、림상특점급다기관손해등방면진행총결분석.결과 634례표본중양성308례,양성솔48.6％,6～12월령양성197례점66.3％,전년균가검출륜상병독,제일계도63.8％、제사계도62.6％,양성솔교고,68.6％반유심기손해,41.2％반유하호흡도감염,13.3％반유간공손해,14.9％반유신장손해,9.4％반유량궐,4.9％반유혈액계통손해.결론 륜상병독시인기소인복사적주요병원,6～12월령적영유인감염솔최고,제일、제사계도시고발계절.륜상병독감염가인기다기관공능손해.
Objective Study on the infection rate,influence factors and clinical characteristic of rotavirus diarrhea in children.Methods 634 hospitalized diarrhea children was collected from 2006 June to 2010 October.The gold immunochromatographic double-antibody sandwiched assay was used to detect the antigen of Rotavirus directly.The age of onset,incidence,clinical features and multiple organ damage and other aspects were summarized and analyzed.Results 308 cases was detected positively in the 634specimens,the positive rate was 48.6％.In 6 to 12 months old children 197 cases was detected positively,accounted for 66.3％.Rotavirus was detected all the year round and the positive rate was higher in the first quarter and the forth quarter and was 63.8％ and 62.6％ respectively.68.6％ accompanied with myocardial damage,41.2％ with lower respiratory tract infection,13.3％ with liver damage,14.9％ with renal damage,9.4％ with convulsions in 4.9％,accompanied by the damage of blood system.Conclusion Rotavirus is the leading cause of pediatric diarrhea the main pathogens,6-12 months infants with the highest infection rate,the first,the fourth quarter is higher.Rotavirus infection can cause multiple organ dysfunction.
