蚌埠医学院学报
蚌埠醫學院學報
방부의학원학보
ACTA ACADEMIAE MEDICINAE BENGBU
2001年
4期
290-291
,共2页
何浩明%黄慧建%徐宁%李小民%田小平%汪洪流
何浩明%黃慧建%徐寧%李小民%田小平%汪洪流
하호명%황혜건%서저%리소민%전소평%왕홍류
糖尿病性血管病%红细胞膜%酶激活
糖尿病性血管病%紅細胞膜%酶激活
당뇨병성혈관병%홍세포막%매격활
目的：探讨2型糖尿病性血管病患者的红细胞膜Na+*K+-ATP酶活性的变化及其意义。方法：按Reilini制膜法测定55例2型糖尿病性血管病红细胞膜Na+*K+ -ATP酶活性，并与35名健康组作对照，并且将其结果与红细胞内Na+*K+浓度、空腹血糖、糖化血红蛋白等进行相关分析。结果：2型糖尿病血管病患者红细胞膜Na+*K+-ATP酶含量显著低于正常人(P＜0.01)，且与红细胞内Na+*K+浓度、空腹血糖、糖化血红蛋白等密切相关。结论：红细胞膜Na+*K+-ATP酶活性的下降可能参与糖尿病性血管病变的发生、发展过程。
目的：探討2型糖尿病性血管病患者的紅細胞膜Na+*K+-ATP酶活性的變化及其意義。方法：按Reilini製膜法測定55例2型糖尿病性血管病紅細胞膜Na+*K+ -ATP酶活性，併與35名健康組作對照，併且將其結果與紅細胞內Na+*K+濃度、空腹血糖、糖化血紅蛋白等進行相關分析。結果：2型糖尿病血管病患者紅細胞膜Na+*K+-ATP酶含量顯著低于正常人(P＜0.01)，且與紅細胞內Na+*K+濃度、空腹血糖、糖化血紅蛋白等密切相關。結論：紅細胞膜Na+*K+-ATP酶活性的下降可能參與糖尿病性血管病變的髮生、髮展過程。
목적：탐토2형당뇨병성혈관병환자적홍세포막Na+*K+-ATP매활성적변화급기의의。방법：안Reilini제막법측정55례2형당뇨병성혈관병홍세포막Na+*K+ -ATP매활성，병여35명건강조작대조，병차장기결과여홍세포내Na+*K+농도、공복혈당、당화혈홍단백등진행상관분석。결과：2형당뇨병혈관병환자홍세포막Na+*K+-ATP매함량현저저우정상인(P＜0.01)，차여홍세포내Na+*K+농도、공복혈당、당화혈홍단백등밀절상관。결론：홍세포막Na+*K+-ATP매활성적하강가능삼여당뇨병성혈관병변적발생、발전과정。
Objective:To study on the change of Na+*K +-ATPase activity of erythrocyte membrane of patients with diabetic type 2 an giopathies.Methods:According to Reilini method the concentrations of erythrocyt e membrane Na+*K+-ATPase of 55 cases with diabetic type 2 angiopathies and 35 normal controls were measured.With density of Na+ and K+,levels of f asting blood glucose(FBG),glycosylated hemoglobin(GHb) were also detected.Results:Na+*K+-ATPase activity of erythrocyte membrane was sig nificantly decreased in diabetic type 2 patients(P＜0.01).Conclusions:Decreased Na+*K+-ATPase activity in erythrocyte me mbrane may be one of factors that contributed to the occurrence and development of diabetic type 2 mellitus.
