国际肿瘤学杂志
國際腫瘤學雜誌
국제종류학잡지
JOURNAL OF INTERNATIONAL ONCOLOGY
2010年
6期
445-448
,共4页
细胞周期%细胞周期蛋白E%周期素依赖蛋白激素抑制剂p27%乳腺肿瘤
細胞週期%細胞週期蛋白E%週期素依賴蛋白激素抑製劑p27%乳腺腫瘤
세포주기%세포주기단백E%주기소의뢰단백격소억제제p27%유선종류
Cell cycle%Cyclin E%Cyclin-dependent kinase inhibitor p27%Breast neoplasms
细胞周期调控紊乱是乳腺癌重要发病机制之一,而cyclin E和p27是细胞周期最重要的调节因子.研究表明,cyclin E和p27具有评估乳腺癌预后的能力,且与其他生物学指标相比,与乳腺癌预后相关性更大.
細胞週期調控紊亂是乳腺癌重要髮病機製之一,而cyclin E和p27是細胞週期最重要的調節因子.研究錶明,cyclin E和p27具有評估乳腺癌預後的能力,且與其他生物學指標相比,與乳腺癌預後相關性更大.
세포주기조공문란시유선암중요발병궤제지일,이cyclin E화p27시세포주기최중요적조절인자.연구표명,cyclin E화p27구유평고유선암예후적능력,차여기타생물학지표상비,여유선암예후상관성경대.
Deregulation of cell cycle is one of important mechanisms leading to breast cancer. It has been revealed that cyclin E and p27 are the most important regulatory factor for cell cycle control and a better marker for evaluating prognosis of breast cancer compared to other biological markers.
