中华内科杂志
中華內科雜誌
중화내과잡지
CHINESE JOURNAL OF INTERNAL MEDICINE
2012年
8期
630-633
,共4页
姚小英%林岩%耿介立%孙亚蒙%陈莺%李焰生
姚小英%林巖%耿介立%孫亞矇%陳鶯%李燄生
요소영%림암%경개립%손아몽%진앵%리염생
卒中%发病年龄%性别分布%危险因素
卒中%髮病年齡%性彆分佈%危險因素
졸중%발병년령%성별분포%위험인소
Stroke%Age of onset%Sex distribution%Risk factors
目的 比较不同性别和年龄的首发脑梗死患者危险因素的分布差异.方法 收集首发脑梗死患者1027例,依年龄分为中青年(<50岁)、中老年(50~ 80岁)和高龄(>80岁)组.危险因素分析包括吸烟、大量饮酒、高血压、糖尿病、心脏病、心房颤动(房颤)和心脑血管疾病家族史.结果 女性患者发病年龄显著大于男性患者(71.1岁比65.7岁,P<0.001),有吸烟和大量饮酒史的比例显著低于男性患者(4.4%比59.9%、1.0%比31.6%,P值均<0.001),但合并糖尿病(26.8%比19.2%)、心脏病(28.8%比19.2%)、房颤史(7.6%比3.9%)的比例显著高于男性患者(P<0.01).首发卒中年龄越大,吸烟和大量饮酒者比例越低;高龄组患者合并心脏病和房颤的比例高,而有心血管疾病家族史的比例较低.中青年组中,女性患者易有心脏病史及心脏病家族史(P=0.015和P=0.048).在中老年组中,女性患者有高血压、糖尿病、心脏病和房颤病史的比例显著高于男性患者(P=0.021,P=0.004,P=0.001和P=0.039).结论 不同性别和年龄的首发脑梗死患者的危险因素分布存在差异,故应针对不同危险因素特征进行筛查和健康教育.
目的 比較不同性彆和年齡的首髮腦梗死患者危險因素的分佈差異.方法 收集首髮腦梗死患者1027例,依年齡分為中青年(<50歲)、中老年(50~ 80歲)和高齡(>80歲)組.危險因素分析包括吸煙、大量飲酒、高血壓、糖尿病、心髒病、心房顫動(房顫)和心腦血管疾病傢族史.結果 女性患者髮病年齡顯著大于男性患者(71.1歲比65.7歲,P<0.001),有吸煙和大量飲酒史的比例顯著低于男性患者(4.4%比59.9%、1.0%比31.6%,P值均<0.001),但閤併糖尿病(26.8%比19.2%)、心髒病(28.8%比19.2%)、房顫史(7.6%比3.9%)的比例顯著高于男性患者(P<0.01).首髮卒中年齡越大,吸煙和大量飲酒者比例越低;高齡組患者閤併心髒病和房顫的比例高,而有心血管疾病傢族史的比例較低.中青年組中,女性患者易有心髒病史及心髒病傢族史(P=0.015和P=0.048).在中老年組中,女性患者有高血壓、糖尿病、心髒病和房顫病史的比例顯著高于男性患者(P=0.021,P=0.004,P=0.001和P=0.039).結論 不同性彆和年齡的首髮腦梗死患者的危險因素分佈存在差異,故應針對不同危險因素特徵進行篩查和健康教育.
목적 비교불동성별화년령적수발뇌경사환자위험인소적분포차이.방법 수집수발뇌경사환자1027례,의년령분위중청년(<50세)、중노년(50~ 80세)화고령(>80세)조.위험인소분석포괄흡연、대량음주、고혈압、당뇨병、심장병、심방전동(방전)화심뇌혈관질병가족사.결과 녀성환자발병년령현저대우남성환자(71.1세비65.7세,P<0.001),유흡연화대량음주사적비례현저저우남성환자(4.4%비59.9%、1.0%비31.6%,P치균<0.001),단합병당뇨병(26.8%비19.2%)、심장병(28.8%비19.2%)、방전사(7.6%비3.9%)적비례현저고우남성환자(P<0.01).수발졸중년령월대,흡연화대량음주자비례월저;고령조환자합병심장병화방전적비례고,이유심혈관질병가족사적비례교저.중청년조중,녀성환자역유심장병사급심장병가족사(P=0.015화P=0.048).재중노년조중,녀성환자유고혈압、당뇨병、심장병화방전병사적비례현저고우남성환자(P=0.021,P=0.004,P=0.001화P=0.039).결론 불동성별화년령적수발뇌경사환자적위험인소분포존재차이,고응침대불동위험인소특정진행사사화건강교육.
Objective To compare distribution difference in risk factors of patients with first-ever ischemic stroke (IS) of different age and gender.Methods A total of 1027 patients admitted to the neurological department in Shanghai Renji Hospital with first-ever IS were recruited and divided into young adult group ( < 50 years old),middle-aged group (50-80 years old),and very old group ( > 80 years old)according to their ages.Risk factor analysis included history of smoking,high alcohol consumption,hypertension (HT),diabetes mellitus (DM),heart diseases,atrial fibrillation (AF) and family history of cardiovascular diseases.Results Female patients were globally older than male patients (71.1 vs 65.7,P < 0.001 ) at the first attack of IS and having higher prevalence of DM (26.8% vs 19.2%,P =0.004 ),heart diseases (28.8% vs 19.2%,P<0.001) and AF (7.6% vs 3.9%,P=0.009).However,female patients were less likely to drink heavily ( 1.0% vs 31.6%,P <0.001 ) or smoke (4.4% vs 59.9%,P <0.001 ) than the male patients.The rates of smoking and heavy drinking in young adult group were higher than that in other two groups.Patients in very old group had higher prevalence of heart diseases and AF but lower proportion of positive family cardiovascular diseases history than patients in other two groups.HT and DM were equally frequent among three groups.In young adult group,female patients were more likely to have heart diseases and family history of heart diseases (P =0.015 and P =0.048).In middle-old group,HT,DM,heart disease and AF were more common in women than in men (P =0.021,P =0.004,P =0.001 and P =0.039).Conclusion There are differences in risk factor distribution in patients with first-ever IS of different age and gender.Therefore,screening and health education should be performed in allusion to different risk factors.