CAJ | 학술논문

目的了解北京地区戊型肝炎(戊肝)病毒感染现状.方法采用EIA诊断试剂检测人群、猪和鸡血清中戊肝病毒(HEV)抗体.结果 1208份人群血清中有260份HEV-IgG抗体阳性,总阳性率为21.52%,对260份HEV IgG阳性血进行IgM抗体检测,有22份阳性,占8.46%.32份猪血清中有15份阳性,阳性率为46.88%,34份鸡血清HEV抗体全部为阴性.人群不同年龄组HEV抗体阳性率依次为11～20岁为5.60%(14/250),21～30岁为20%(42/210),31～40岁为24.03%(62/258),41～50岁为26.44%(78/295),51～60岁为32.82%(64/195),男女不同性别HEV感染率比较,男性阳性率为29.51%(144/488),女性为21.70%(102/470).结论北京地区人群和与人接触密切的家畜猪均存在戊肝病毒感染,人群戊肝病毒感染率随年龄增长而升高,尤其是男性戊肝病毒感染率明显高于女性,郊区流动人群戊肝病毒感染率明显高于市内人群,家畜猪感染率是人群的2倍以上.
목적 료해북경지구무형간염(무간)병독감염현상.방법 채용EIA진단시제검측인군、저화계혈청중무간병독(HEV)항체.결과 1208빈인군혈청중유260빈HEV-IgG항체양성,총양성솔위21.52%,대260빈HEV IgG양성혈진행IgM항체검측,유22빈양성,점8.46%.32빈저혈청중유15빈양성,양성솔위46.88%,34빈계혈청HEV항체전부위음성.인군불동년령조HEV항체양성솔의차위11～20세위5.60%(14/250),21～30세위20%(42/210),31～40세위24.03%(62/258),41～50세위26.44%(78/295),51～60세위32.82%(64/195),남녀불동성별HEV감염솔비교,남성양성솔위29.51%(144/488),녀성위21.70%(102/470).결론 북경지구인군화여인접촉밀절적가축저균존재무간병독감염,인군무간병독감염솔수년령증장이승고,우기시남성무간병독감염솔명현고우녀성,교구류동인군무간병독감염솔명현고우시내인군,가축저감염솔시인군적2배이상.
Objective To investigate the seroprevalence of HEV infection in human population, swine and chicken in Beijing region. Methods EIA was used for detecting anti-HEV IgG of the serum samples. All samples were collected in 2006-2007 in Beijing areas. Results The anti-HEV IgG was detected positive in 21.52% of human(260/1208), 46.88 % (15/32)of swine, but was negative in chickens (0/24). The positive rate of human at different age group, was 5.60% (14/250)of 11-20 year, 20% (42/210)of 21-30 year,24.03% (62/258)of 31-40 year, 26.44% (78/295)of 41-50 year, 32.82% (64/195)of 51-60 year. The male(29.51% ) was higher than the female (21.70%). Conclusion The HEV infection was correlation with age and sex significandy. The infection rate was increased with age, the positive rate in swine was more double than the human population.