CAJ | 학술논문

目的:观察高压氧治疗对兔腰椎横突问融合的影响.方法:取28只健康成年雌性白兔,行双侧腰5～6横突间融合.随机分为高压氧治疗组和对照组.术后6周处死动物取腰段脊柱行手术检查、X线摄片、骨密度测定和组织学检查.结果:手术检查结果和X线摄片分析结果显示高压氧治疗组融合率显著高于对照组(P<0.05).骨密度测定结果显示高压氧治疗组骨密度值显著高于对照组(P<0.05).组织学观察显示高压氧治疗组的新生骨较对照组多和成熟.结论:高压氧治疗能提高兔腰椎横突间融合的融合率.
목적:관찰고압양치료대토요추횡돌문융합적영향.방법:취28지건강성년자성백토,행쌍측요5～6횡돌간융합.수궤분위고압양치료조화대조조.술후6주처사동물취요단척주행수술검사、X선섭편、골밀도측정화조직학검사.결과:수술검사결과화X선섭편분석결과현시고압양치료조융합솔현저고우대조조(P<0.05).골밀도측정결과현시고압양치료조골밀도치현저고우대조조(P<0.05).조직학관찰현시고압양치료조적신생골교대조조다화성숙.결론:고압양치료능제고토요추횡돌간융합적융합솔.
Objective To observe the effect of hyperbaric oxygen (HBO) therapy on lumbar intertransverse fusion in rabbits. Methods Twenty-eight healthy adult female rabbits underwent lum-bar intertransverse fusion at L5～6 with autogenous iliac bone graft. They were randomly assigned into an HBO group and a control group (n=14). Rabbits were killed 6 weeks after the operation for surgical inspection, X-ray, bone density measurement and histologic analysis. Results The fusion rate of the HBO group evaluated by surgical inspection, and radiologic examination in a blind fashion significantly increased compared with that of the control group (P<0.05). Qualitative histologic as-sessment showed increased bone formation and bone maturity in the HBO group compared with the control group. Conclusion Hyperbaric oxygen therapy could improve the fusion rate of lumbar inter-transverse fusion in rabbits.