CAJ | 학술논문

背景: 前期实验数据证明,水牛角胎的形态结构、理化参数、生物性质、力学性能等方面具有良好的骨科生物材料的特征.目的: 拟观察脱蛋白处理水牛角胎后,其抗原性和生物力学强度与经30%H2O2处理的时间关系.设计、时间及地点: 测量实验,于2000-02/03在昆明理工大学力学试验室完成.材料: 水牛来源于云南省泸西县屠宰场,取水牛角胎制成公称尺寸试件.方法: 试件经热蒸馏水反复冲洗后,用氯仿-甲醇1:1浸渍48h,再用体积分数为0.3的H2O2浸渍,实验组分别处理24,48h,另设未经任何处理试件为对照组.主要观察指标: 电测试法测定弹性模量E;直接加压法测其抗压强度.结果: 各组间弹性模量相比,差异均无显著性意义(P>0.05).对照组的抗压强度明显高于实验组(P<0.01),24h实验组与48h实验组间抗压强度相比,差异无显著性意义(P>0.05).结论: 水牛角胎经H2O2浸渍48h处理,保留了较好的生物力学强度.
배경: 전기실험수거증명,수우각태적형태결구、이화삼수、생물성질、역학성능등방면구유량호적골과생물재료적특정.목적: 의관찰탈단백처리수우각태후,기항원성화생물역학강도여경30%H2O2처리적시간관계.설계、시간급지점: 측량실험,우2000-02/03재곤명리공대학역학시험실완성.재료: 수우래원우운남성로서현도재장,취수우각태제성공칭척촌시건.방법: 시건경열증류수반복충세후,용록방-갑순1:1침지48h,재용체적분수위0.3적H2O2침지,실험조분별처리24,48h,령설미경임하처리시건위대조조.주요관찰지표: 전측시법측정탄성모량E;직접가압법측기항압강도.결과: 각조간탄성모량상비,차이균무현저성의의(P>0.05).대조조적항압강도명현고우실험조(P<0.01),24h실험조여48h실험조간항압강도상비,차이무현저성의의(P>0.05).결론: 수우각태경H2O2침지48h처리,보류료교호적생물역학강도.
BACKGROUND: Previous research reveals that, the morphous, structure, physicochemical property and mechanical characteristics of matrix in buffalo cornu all contribute to the biomaterials in the field of orthopaedics.OBJECTIVE: To investigate the correlation between the duration of matrix in buffalo cornu soaked in 30% hydrogen peroxide and the antigenicity, the biomechanical intensity of matrix in buffalo cornu treated by deproteinization.DESIGN, TIME AND SETTING: Measurement experiments were performed in the Mechanics Laboratory, Kunming University of Science and Technology (Kunming, Yunnan, China) from February to March in 2000.MATERIALS: Buffalo was provided by Luxi Abattoir of Yunnan Province (China), and then processed into test pieces at a nominal thickness.METHODS: The metric test pieces were rinsed with distilled water and soaked by chloroform-methyl alcohol at a ratio of 1:1 for 48 hours, then in 30% hydrogen peroxide for 24 and 48 hours, which served as the experimental group. While those remaining untreated were taken as controls.MAIN OUTCOME MEASURES: The modulus of elasticity and compressive strength were measured by electric measurement method and direct pressurization method, respectively.RESULTS: The modulus of elasticity between the experimental group and the control group had no significant difference (P>0.05). The compressive strength in the control group was significantly higher than that in the experimental group (P<0.01), and there were no significant differences between the experimental group treated for 24 hours and the experimental group treated for 48 hours (P>0.05).CONCLUSION: Subsequent to soaking in 30% hydrogen peroxide for 48 hours, the matrix in buffalo cornu maintains better biomechanicai intensity.