合成化学
閤成化學
합성화학
CHINESE JOURNAL OF SYNTHETIC CHEMISTRY
2009年
6期
755-756,763
,共3页
武明芬%施培基%王荣先%周晓靓%王浩
武明芬%施培基%王榮先%週曉靚%王浩
무명분%시배기%왕영선%주효정%왕호
苯胺%苯甲酰氯%苯并噻唑%药物合成
苯胺%苯甲酰氯%苯併噻唑%藥物閤成
분알%분갑선록%분병새서%약물합성
anilin%benzoyl chloride%benzothiazole%drug systhesis
以对甲氧基苯胺和对硝基苯甲酰氯为起始原料,经4步反应合成了2-(4'-氨基苯基)-6-羟基苯并噻唑,总收率50.4%,纯度99.72%,其结构经~1H NMR和HR-MS表征.
以對甲氧基苯胺和對硝基苯甲酰氯為起始原料,經4步反應閤成瞭2-(4'-氨基苯基)-6-羥基苯併噻唑,總收率50.4%,純度99.72%,其結構經~1H NMR和HR-MS錶徵.
이대갑양기분알화대초기분갑선록위기시원료,경4보반응합성료2-(4'-안기분기)-6-간기분병새서,총수솔50.4%,순도99.72%,기결구경~1H NMR화HR-MS표정.
2-(4'-Aminophenyl)-6-hydroxybenzothiazole in total yield of 50.4% with purity of 99.72% was synthesized from p-methoxyaniline and p-nitrobenzoyl chloride by a four-step reaction. The structure was characterized by ~1H NMR and HR-MS.
