CAJ | 학술논문

核受体是配体依赖性转录因子超家族,对脂类代谢基因有重要的转录调控作用,与许多代谢性疾病密切相关,近年来,国内外对核受体在脂类代谢中调控作用的广泛研究,有助于进一步加深对胆固醇结石病等与脂类代谢相关疾病的发病机制认识.
핵수체시배체의뢰성전록인자초가족,대지류대사기인유중요적전록조공작용,여허다대사성질병밀절상관,근년래,국내외대핵수체재지류대사중조공작용적엄범연구,유조우진일보가심대담고순결석병등여지류대사상관질병적발병궤제인식.
Nuclear receptors,the superfamily of ligand-activated transcription factors,play crucial role in the regulation of gene expression of the lipid metabolism,and are involved in many metabolic diseases,such as cholesterol gallstone disease.Recently many domestic and foreign researches on the role of nuclear receptors in the lipid metabolism,help to further elucidate the biomolecular pathogenesis of cholesterol gallstone disease and other diseases associated with the lipid metabolism.