CAJ | 학술논문

Lemierre综合征是源自感染性栓塞性颈内静脉炎的急性、全身性、化脓性疾病,坏死梭菌是最主要致病菌,最常继发于口咽感染.由于可累及全身各脏器,临床表现无特异性,极易误诊、漏诊.根据感染性栓塞性颈内静脉炎的症状、体征或影像学检查结果,结合血行感染或远处化脓病灶证据,可明确诊断.推荐早期、足量、足疗程并且覆盖厌氧菌的联合抗感染治疗.
Lemierre종합정시원자감염성전새성경내정맥염적급성、전신성、화농성질병,배사사균시최주요치병균,최상계발우구인감염.유우가루급전신각장기,림상표현무특이성,겁역오진、루진.근거감염성전새성경내정맥염적증상、체정혹영상학검사결과,결합혈행감염혹원처화농병조증거,가명학진단.추천조기、족량、족료정병차복개염양균적연합항감염치료.
Lemierre syndrome is an acute systemic suppurative infection originating from internal jugular vein septic thrombophlebitis most commonly as sequel to oropharyngeal infection, with Fusobaeterium necrophorum as its most common pathogen. It is prone to misdiagnosis or under-diagnosis due to its lack of specific clinical manifestations, arising from multi-organ involvement. Diagnosis can be established based on positive findings of internal jugular vein septic thrombophlebitis from history collection,physical examination or imaging studies, in combination with evidence of hematogenous infection or metastatic abscesses. Early, sufficient and prolonged course of antimicrobial therapy covering anaerobic bacteria is recommended.