CAJ | 학술논문

目的探讨老年高血压患者高尿酸血症与缺血性脑卒中发生的相关性.方法分析100例60岁以上老年原发性高血压患者,根据尿酸水平分为对照组(尿酸≤417 μmol/L,51例)和实验组(尿酸≥417 μmol/L,49例),比较两组血尿酸水平与缺血性脑卒中之间的关系.结果两组在年龄、体质指数(BMI)、饮酒史、糖尿病史等一般情况方面差异无统计学意义(P＞0.05).入院时的尿酸水平,吸烟史及脑卒中发生率差异有统计学意义(P＜0.05).实验组不同时间段各组间尿酸和脑卒中严重程度评分均有统计学意义(P＜0.05).Logistic回归分析发现,调整脑卒中的其他危险因素后,实验组的脑卒中的发生率是对照组的2.88倍(β=1.059,OR=2.884,P=0.03).结论尿酸水平增高与老年原发性高血压患者脑卒中发生密切相关.
목적 탐토노년고혈압환자고뇨산혈증여결혈성뇌졸중발생적상관성.방법 분석100례60세이상노년원발성고혈압환자,근거뇨산수평분위대조조(뇨산≤417 μmol/L,51례)화실험조(뇨산≥417 μmol/L,49례),비교량조혈뇨산수평여결혈성뇌졸중지간적관계.결과 량조재년령、체질지수(BMI)、음주사、당뇨병사등일반정황방면차이무통계학의의(P＞0.05).입원시적뇨산수평,흡연사급뇌졸중발생솔차이유통계학의의(P＜0.05).실험조불동시간단각조간뇨산화뇌졸중엄중정도평분균유통계학의의(P＜0.05).Logistic회귀분석발현,조정뇌졸중적기타위험인소후,실험조적뇌졸중적발생솔시대조조적2.88배(β=1.059,OR=2.884,P=0.03).결론 뇨산수평증고여노년원발성고혈압환자뇌졸중발생밀절상관.
Objective To investigate the relationship between blood uric acid and ischemic stroke in the elderly with hypertension.Methods Totally 100 elderly patients with hypertension were divided into study group (blood uric acid≥417 μmol/L,n=49) and control group (blood uric acid＜417 μmol/L,n=51).The relationship between the level of uric acid and ischemic stroke were analyzed in two groups.Results There were not significant differences in age,body mass index (BMI),smoking and drinking,diabetes(P＞0.05)between the groups,but there were differences in uric acid levels,smoking history,and stroke incidence at admission into hospital(P＜0.05).In study group,uric acid and stroke severity score were significantly related in different times(P＜0.05).After adjusting the related risk factors,logistic multiple regression analysis showed that the odd ratio of ischemic stroke was greater in study group than in control group (β=1.059,OR =2.884,P=0.03).