CAJ | 학술논문

目的观察中药血必净注射液对中老年带状疱疹患者神经痛的干预效果.方法选择80例中老年带状疱疹患者,将其随机分为治疗组(40例)和对照组(40例).两组患者均口服万乃洛韦、布洛芬胶囊,外涂三黄洗剂.治疗组另加用血必净注射液静脉滴注,疗程2周.比较两组患者治疗后的临床症状积分、临床疗效及疼痛程度.结果两组共75例患者完成疗程,治疗组38例,对照组37例.治疗后两组患者疼痛、皮损+疼痛的评分间差异均有统计学意义(P＜0.01).治疗后治疗组患者临床痊愈12例,显效14例,有效10例,无效2例;对照组临床痊愈8例,显效9例,有效12例,无效8例,两组患者疗效间差异有统计学意义(z=2.03,P=0.04).治疗后治疗组患者视觉模拟尺度评分(VAS)为(4.0±1.3)分,对照组为(4.8±1.4)分,差异有统计学意义(t=2.62,P＜0.05).结论血必净注射液能改善中老年带状疱疹患者神经痛,从而提高临床疗效.
목적 관찰중약혈필정주사액대중노년대상포진환자신경통적간예효과.방법 선택80례중노년대상포진환자,장기수궤분위치료조(40례)화대조조(40례).량조환자균구복만내락위、포락분효낭,외도삼황세제.치료조령가용혈필정주사액정맥적주,료정2주.비교량조환자치료후적림상증상적분、림상료효급동통정도.결과 량조공75례환자완성료정,치료조38례,대조조37례.치료후량조환자동통、피손+동통적평분간차이균유통계학의의(P＜0.01).치료후치료조환자림상전유12례,현효14례,유효10례,무효2례;대조조림상전유8례,현효9례,유효12례,무효8례,량조환자료효간차이유통계학의의(z=2.03,P=0.04).치료후치료조환자시각모의척도평분(VAS)위(4.0±1.3)분,대조조위(4.8±1.4)분,차이유통계학의의(t=2.62,P＜0.05).결론 혈필정주사액능개선중노년대상포진환자신경통,종이제고림상료효.
Objective To observe the effect of Xuebijing injection on neuralgia in middle- and old-aged patients with herpes zoster(HZ).Methods Eighty middle- and old-aged HZ patients were divided randomly into groups treatment and control,40 in each.Both were given oral valaciclovir and ibuprofen capsules,externally-used Sanhuang lotion.Treatment group were given additional iv gtt Xuebijing,2 weeks.Clinical symptom scores,efficacies and pain degrees were compared.Results A total of 75 patients finished treatment in 2 groups,38 in treatment group,37 in control.There was significant difference in scores of pains,skin lesions with pains between 2 groups(P＜0.01).After treatment,12 were clinically cured,14 improved,10 with effect and 2 without in treatment group,and 8,9,12,8,respectively,in control group,the difference was significant(z=2.03,P=0.04).The visual analogue scale(VAS) score after treatment was (4.0±1.3) in treatment group,(4.8±1.4) in control,the difference was significant(t=2.62,P＜0.05).Conclusion Xuebijing injection can improve neuralgia in middle- and old-aged HZ patients,thus to enhance clinical curative effect.