CAJ | 학술논문

目的探讨准分子激光原位角膜磨镶术(LASIK)后出现角膜铁质沉着的发生率及临床特征及其相关因素.方法搜集行LASIK手术患者39例(78眼),描述角膜铁质沉着特征,并分析其与术后时间、术前屈光度、泪膜破裂时间、泪膜分泌量结果及干眼症状的相关性.结果 78眼中有53眼(67.9％)发现有角膜铁质沉着,位于角膜上皮细胞层基底细胞部位,颜色从淡黄色到黄褐色均有,形状有环状、片状、条索状、点状等,均位于角膜中央,与相应角膜地形图对照,铁质沉着部分为角膜经切削后最低部位,即角膜曲率最小部位,或者为角膜切削边缘,即角膜曲率变化最大部位,也就是角膜最陡峭部位.角膜铁质沉着的出现与手术前屈光度、手术后时间呈正相关[r=0.410,P＜0.01;r =0.398,P＜0.01],与BUT、泪液分泌量、干眼症状之间无明显相关.结论角膜铁质沉着是LASIK术后的临床体征之一,可能与LASIK术后泪池的形成有关,但其发生机制尚需进一步深入研究.
목적 탐토준분자격광원위각막마양술(LASIK)후출현각막철질침착적발생솔급림상특정급기상관인소.방법 수집행LASIK수술환자39례(78안),묘술각막철질침착특정,병분석기여술후시간、술전굴광도、루막파렬시간、루막분비량결과급간안증상적상관성.결과 78안중유53안(67.9％)발현유각막철질침착,위우각막상피세포층기저세포부위,안색종담황색도황갈색균유,형상유배상、편상、조색상、점상등,균위우각막중앙,여상응각막지형도대조,철질침착부분위각막경절삭후최저부위,즉각막곡솔최소부위,혹자위각막절삭변연,즉각막곡솔변화최대부위,야취시각막최두초부위.각막철질침착적출현여수술전굴광도、수술후시간정정상관[r=0.410,P＜0.01;r =0.398,P＜0.01],여BUT、루액분비량、간안증상지간무명현상관.결론 각막철질침착시LASIK술후적림상체정지일,가능여LASIK술후루지적형성유관,단기발생궤제상수진일보심입연구.
Objective To report the occurrence and features of corneal iron deposition after laser in situ keratomileusis (LASIK).Methods We evaluated 78 eyes undergoing LASIK.Corneal iron deposition was analyzed with respect to preoperative spherical equivalent,postoperative time interval,subjective complaints of dry eye tear break-up time(BUT) and Schirmer's I test.Results There were 67.9 ％ of 78 eyes displaying a distinctive corneal iron deposition of variable density in a ring or patch configuration in the middle zone in the corneal basal epithelial cells.The appearance of this iron deposition was correlated positively with time after surgery and preoperative spherical equivalent.Conclusions Corneal iron deposition in a ring or patch can be associated with previous LASIK surgery.This iron deposition within the margin of the ablated zone or in the flatted zone develops from tear pooling after LASIK.