中华儿科杂志
中華兒科雜誌
중화인과잡지
Chinese Journal of Pediatrics
2012年
2期
83-92
,共10页
中国儿童慢性咳嗽病因构成比研究协作组
中國兒童慢性咳嗽病因構成比研究協作組
중국인동만성해수병인구성비연구협작조
病因构成比%咳嗽%儿童
病因構成比%咳嗽%兒童
병인구성비%해수%인동
Causes constituents ratio%Cough%Child
目的 了解中国儿童慢性咳嗽的病因分布及构成比,推动其诊治的标准化和规范化.方法 根据2008年中华医学会儿科学分会呼吸学组制定的《儿童慢性咳嗽诊断和治疗指南》,设计儿童慢性咳嗽病因调查表,组织全国19个省、直辖市、自治区共29所医院前瞻性入组慢性咳嗽病例并完成3个月随访；对汇总的各项数据统计分析、得出全国儿童慢性咳嗽病因构成比等.结果 实际入组病例数共4582例,合格病例4529例,合格率98.80％.列病因构成比前3位的分别是咳嗽变异性哮喘1900例(41.95％)、上气道咳嗽综合征1119例(24.71％)、呼吸道感染和感染后咳嗽984例(21.73％).胃食管反流28例(占0.62％)；其他病因者498例(11.00％),其中多病因者占387例(8.54％),首位是上气道咳嗽综合征合并有咳嗽变异性哮喘(占50.13％),其次是呼吸道感染和感染后咳嗽合并上气道咳嗽综合征占(26.10％).总诊断修正率18.83％.不同病因在不同性别间和不同年龄间的分布是有显著差异的,不同病因致慢性咳嗽的好发时相各有特点.结论 中国儿童慢性咳嗽的主要病因构成比依次为咳嗽变异性哮喘、上气道咳嗽综合征、呼吸道感染和感染后咳嗽和其他各种病因,要注意多病因和病因未明的病例.不同年龄和不同性别组儿童慢性咳嗽病因构成比是不同的.要重视观察、等待和随访的原则.
目的 瞭解中國兒童慢性咳嗽的病因分佈及構成比,推動其診治的標準化和規範化.方法 根據2008年中華醫學會兒科學分會呼吸學組製定的《兒童慢性咳嗽診斷和治療指南》,設計兒童慢性咳嗽病因調查錶,組織全國19箇省、直轄市、自治區共29所醫院前瞻性入組慢性咳嗽病例併完成3箇月隨訪；對彙總的各項數據統計分析、得齣全國兒童慢性咳嗽病因構成比等.結果 實際入組病例數共4582例,閤格病例4529例,閤格率98.80％.列病因構成比前3位的分彆是咳嗽變異性哮喘1900例(41.95％)、上氣道咳嗽綜閤徵1119例(24.71％)、呼吸道感染和感染後咳嗽984例(21.73％).胃食管反流28例(佔0.62％)；其他病因者498例(11.00％),其中多病因者佔387例(8.54％),首位是上氣道咳嗽綜閤徵閤併有咳嗽變異性哮喘(佔50.13％),其次是呼吸道感染和感染後咳嗽閤併上氣道咳嗽綜閤徵佔(26.10％).總診斷脩正率18.83％.不同病因在不同性彆間和不同年齡間的分佈是有顯著差異的,不同病因緻慢性咳嗽的好髮時相各有特點.結論 中國兒童慢性咳嗽的主要病因構成比依次為咳嗽變異性哮喘、上氣道咳嗽綜閤徵、呼吸道感染和感染後咳嗽和其他各種病因,要註意多病因和病因未明的病例.不同年齡和不同性彆組兒童慢性咳嗽病因構成比是不同的.要重視觀察、等待和隨訪的原則.
목적 료해중국인동만성해수적병인분포급구성비,추동기진치적표준화화규범화.방법 근거2008년중화의학회인과학분회호흡학조제정적《인동만성해수진단화치료지남》,설계인동만성해수병인조사표,조직전국19개성、직할시、자치구공29소의원전첨성입조만성해수병례병완성3개월수방；대회총적각항수거통계분석、득출전국인동만성해수병인구성비등.결과 실제입조병례수공4582례,합격병례4529례,합격솔98.80％.렬병인구성비전3위적분별시해수변이성효천1900례(41.95％)、상기도해수종합정1119례(24.71％)、호흡도감염화감염후해수984례(21.73％).위식관반류28례(점0.62％)；기타병인자498례(11.00％),기중다병인자점387례(8.54％),수위시상기도해수종합정합병유해수변이성효천(점50.13％),기차시호흡도감염화감염후해수합병상기도해수종합정점(26.10％).총진단수정솔18.83％.불동병인재불동성별간화불동년령간적분포시유현저차이적,불동병인치만성해수적호발시상각유특점.결론 중국인동만성해수적주요병인구성비의차위해수변이성효천、상기도해수종합정、호흡도감염화감염후해수화기타각충병인,요주의다병인화병인미명적병례.불동년령화불동성별조인동만성해수병인구성비시불동적.요중시관찰、등대화수방적원칙.
Objective To understand the causes of chronic cough in children in China and the composition ratio of the distribution and to promote the standardization and normalization of its treatment.Method According to the 2008 Guidelines of diagnosis and treatment of chronic cough in children that were formulated by The Subspecialty Group of Respiratory Diseases,The Society of Pediatrics,Chinese Medical Association and the editorial board of Chinese Journal of Pediatrics we designed the questionnaire of the causes of chronic cough in children and organized 29 hospitals in 19 provinces,municipalities and autonomous regions to enroll cases with chronic cough and completed 3-month follow-up.The data were statistically analyzed and the causes constituents ratio of chronic cough was obtained. Result Of 4582cases,4529 were eligible( the passing rate of 98.8％ ).The leading 3 causes were cough variant asthma (CVA) in 1900 cases ( 41.95％ ),upper airway cough syndrome (UACS) in 1119 cases ( 24.71％ ),respiratory infections and post-infectious cough ( PIC ) in 984 cases ( 21.73％ ). Gastroesophageal reflux cough (GERC) found in 28 cases ( accounting for 0.62％ ) ; other causes were 498 cases ( 11％ ),in which 387 cases (8.54％) had multiple etiologies.The leading cause in UACS associated with CVA,which accounted for 50.13％,followed by PIC with UACS accounting for 26.10％.The total correct diagnosis rate was 18.83％.Among different causes in different gender and age distribution were significantly different.Conclusion The main causes of chronic cough in Chinese children are CVA,UACS,PIC and other causes.We should pay attention to the causes and cases of unknown etiology.Children in different age and gender groups have different constitute ratio of cause of chronic cough.
