CAJ | 학술논문

目的探讨CT在125I粒子组织间植入治疗肿瘤中的作用与技术优势.方法收集无法手术根治而行CT导引下125I粒子组织间植入治疗肿瘤患者45例51个病灶57例次.术后1、2、6个月复查CT,了解病变进展情况.结果粒子植入术均一次成功,总有效率达74.5%,无严重并发症.术后即刻CT扫描显示粒子在瘤体内分布满意者50例次,其余7例次CT扫描显示粒子分布欠满意,包括粒子相互重叠、位置过于靠近病灶边缘、较大的放射冷点等,术后1、2、3个月复查CT,CT横断图像均可准确显示粒子在瘤体内外的分布、评价粒子精确位置、间距以及粒子与瘤体、瘤周组织关系、肿瘤体积变化及内部结构坏死液化情况,但对粒子准确计数尚需结合多平面重建图像和定位片.结论 CT导引下125I粒子组织间植入治疗肿瘤是一种安全、可靠、有效的微创治疗方法;CT在粒子植入术前治疗计划制定、术中精确引导、术后质量验证及疗效评估等方面具有较大的作用和应用优势.
목적 탐토CT재125I입자조직간식입치료종류중적작용여기술우세.방법 수집무법수술근치이행CT도인하125I입자조직간식입치료종류환자45례51개병조57례차.술후1、2、6개월복사CT,료해병변진전정황.결과 입자식입술균일차성공,총유효솔체74.5%,무엄중병발증.술후즉각CT소묘현시입자재류체내분포만의자50례차,기여7례차CT소묘현시입자분포흠만의,포괄입자상호중첩、위치과우고근병조변연、교대적방사랭점등,술후1、2、3개월복사CT,CT횡단도상균가준학현시입자재류체내외적분포、평개입자정학위치、간거이급입자여류체、류주조직관계、종류체적변화급내부결구배사액화정황,단대입자준학계수상수결합다평면중건도상화정위편.결론 CT도인하125I입자조직간식입치료종류시일충안전、가고、유효적미창치료방법;CT재입자식입술전치료계화제정、술중정학인도、술후질량험증급료효평고등방면구유교대적작용화응용우세.
Objective To evaluate the role and technical advantages of CT in 125Ⅰseed implantation in the treatment of tumors. Methods CT-guided 125Ⅰ seed implantation in 45 cases of cancer patients treated 57 times in 51 lesions,CT were used to evaluate the progress of lesions after 125Ⅰ seed implantation 1,2,6 months. Results All procedures were once successful and the total effective rate was 74.5% without any serious complications. Fifty CT examinations immediately after implantation showed satisfactorily seeds distribution but seven cases less satisfactorily that include particles overlap,the location is too close to the lesion edge,the larger the radiation cold spots,etc. Follow-up CT reexamination in 1,2 and 6 months demonstrated that CT examinations showed satisfactorily seeds distribution but accurate seeds number,which could be solved by combined with MPR images and the positioning piece. Conclusions CT-guided 125Ⅰ seed implantation treatment of tumors was a safe,reliable and effective minimally invasive treatment. CT in the preoperative treatment of seed implants planning,precise intraoperative guidance,quality assurance and efficacy of postoperative assessment had a greater role and application advantages.