CAJ | 학술논문

目的应用智能声学定量(AQi) 和彩色室壁运动(CK) 技术，对多巴酚丁胺负荷超声心动图（DSE）诱发的冠心病室壁运动异常（W MA）及左室功能改变进行检测，旨在为冠心病早期诊断提供更准确的可定量方法。方法对临床可疑冠心病患者45例，进行AQi-CK-DSE检查，并与冠脉造影结果进行对照。结果用药后心率、收缩压、心率与收缩压的乘积均明显增高；冠心病组射血分数、峰值充盈率减少，峰值充盈时间延长。室壁运动计分指数明显增加（P<0. 001）。DSE诊断冠心病的敏感性、特异性、准确性及一致性指标分别为96.5%、93 .7%、95.5%及90.3%。阳性、阴性预测值分别为96.5%和93.7%。结论 AQi-CK-DSE检测冠心病患者WMA及左心功能的改变，为冠心病早期诊断提供了一种安全准确可定量的方法。
목적응용지능성학정량(AQi) 화채색실벽운동(CK) 기술，대다파분정알부하초성심동도（DSE）유발적관심병실벽운동이상（W MA）급좌실공능개변진행검측，지재위관심병조기진단제공경준학적가정량방법。방법대림상가의관심병환자45례，진행AQi-CK-DSE검사，병여관맥조영결과진행대조。결과용약후심솔、수축압、심솔여수축압적승적균명현증고；관심병조사혈분수、봉치충영솔감소，봉치충영시간연장。실벽운동계분지수명현증가（P<0. 001）。DSE진단관심병적민감성、특이성、준학성급일치성지표분별위96.5%、93 .7%、95.5%급90.3%。양성、음성예측치분별위96.5%화93.7%。결론 AQi-CK-DSE검측관심병환자WMA급좌심공능적개변，위관심병조기진단제공료일충안전준학가정량적방법。
Objective　Using color kinesis (CK) and intell igent acoustic quantification (AQi),regional wall motion abnormality (WMA) and t he left ventricular function variation induced by dobutamine stress test (DST) coronary artery disease (CAD) were detected in order to make a quantification me thod for the early diagnosis of CAD.Methods　Forty-five subjects with suspected CAD underwent dobuta mine stress CK and AQi echocardiograhic test (CK-AQi-DSE) and their results w ere compared with those from coronary anteriography.Results　After dobutamine infusion the heart rate, systolic press ure, and rate-pressure product (RPP) were increased markedly. The ejection frac tion (EF) and peak filling rate (PFR) were decreased and the time of peak fillin g rate (TPFR) was prolonged. Meanwhile the wall motion score index was increased significantly. The sensitivity, specificity, accuray and concordance of DSE for CAD detection were 96.5%, 93.7%, 95.5%, and 90.3%, respectively .Conclusions　AQi-CK-DSE is a realiable and quantitative method to analyse the left ventricular function and WMA of CAD.