CAJ | 학술논문

采用转蓝法测定了药剂学实验中学生自制阿司匹林片的溶出度,以判断制剂溶出度是否合格。结果分析表明：2005级药物制剂班制备的阿司匹林片测得数据为49.03%±5.03%,2005级药学班制备的阿司匹林片测得数据为29.68%±11.42%,均小于80%,溶出度不合格。进行因果分析后,严格规范操作,更换黏合剂后,教师制备的阿司匹林片测得数据为82%±6.23%,大于80%,得到溶出度合格的产品。
채용전람법측정료약제학실험중학생자제아사필림편적용출도,이판단제제용출도시부합격。결과분석표명：2005급약물제제반제비적아사필림편측득수거위49.03%±5.03%,2005급약학반제비적아사필림편측득수거위29.68%±11.42%,균소우80%,용출도불합격。진행인과분석후,엄격규범조작,경환점합제후,교사제비적아사필림편측득수거위82%±6.23%,대우80%,득도용출도합격적산품。
The dissolution rate of aspirin was determined with rotating basket method to judge whether the dissolution was qualified,and the aspirin was made by students in Pharmacy.The dissolution data of aspirin tablets were 49.03%±5.03%（obtained by 2005 pharmaceutical class）,29.68%±11.42%（obtained by 2005 pharmacy class）,all of less than 80%,and the dissolution data of aspirin tablets made by teacher with ameliorated method was 82%±6.23%,above 80%.The dissolution of aspirin tablets was not qualified made by student,and the dissolution of aspirin tablets made by teacher was up to standard after strictly operation regulation and replacement of adhesives.