CAJ | 학술논문

目的:探讨慢性肾衰竭维持性血液透析(MHD)患者颈动脉钙化情况并分析相关因素.方法:对35例MHD患者应用彩色B型超声仪观测双侧颈动脉内膜-中膜厚度(IMT)及钙化情况,同时记录透析龄、收缩压、脉压差,抽血检测血钙、磷、血胆固醇、三酰甘油、白蛋白、C反应蛋白(CRP)、甲状旁腺素,并计算钙磷乘积.结果:35例终末期肾病(ESRD)患者18例(51.4%)存在颈动脉钙化.钙化组IMT值较无钙化组显著增高(P<0.01),透析龄、收缩压、脉压差、血磷、钙磷乘积、CRP较无钙化组明显增高(P<0.05),而钙化组血浆白蛋白较无钙化组显著降低(P<0.05).结论:IMT值、透析龄、血磷、钙磷乘积增高是颈动脉钙化的主要影响因素,收缩压、脉压差、CRP升高和低血浆白蛋白与颈动脉钙化密切相关.MHD患者存在较高的颈动脉钙化率.
목적:탐토만성신쇠갈유지성혈액투석(MHD)환자경동맥개화정황병분석상관인소.방법:대35례MHD환자응용채색B형초성의관측쌍측경동맥내막-중막후도(IMT)급개화정황,동시기록투석령、수축압、맥압차,추혈검측혈개、린、혈담고순、삼선감유、백단백、C반응단백(CRP)、갑상방선소,병계산개린승적.결과:35례종말기신병(ESRD)환자18례(51.4%)존재경동맥개화.개화조IMT치교무개화조현저증고(P<0.01),투석령、수축압、맥압차、혈린、개린승적、CRP교무개화조명현증고(P<0.05),이개화조혈장백단백교무개화조현저강저(P<0.05).결론:IMT치、투석령、혈린、개린승적증고시경동맥개화적주요영향인소,수축압、맥압차、CRP승고화저혈장백단백여경동맥개화밀절상관.MHD환자존재교고적경동맥개화솔.
Objective: To investigate prevalence and correlation factors of carotid calcification and in maintenance hemodialy-sis patients. Methods:The intima- media thickness (IMT) and calcification degree of bilateral carotid artery were detected by ultra-sonography in 35 maintenance hernodialysis (MHD) patients. Years on hernodialysis, systolic/pulse blood pressure, serum calcium/phosphorus and its product, serum lipid profile, C-reaction protein(CRP), intact- parathyroid hormone(i-PTH) were checked at the same time. Results: Carotid calcification was confirmed in 18 of 35 MHD patients (51.4%). 1MT( P< 0.01 ), years on hemodial-ysis, systolic/pulse blood pressure, serum calcium phosphorus product, CPR were significantly higher (P < 0.05) and serum albumin was significantly lower(P<0.05) in patients with carotid calcification than those in patients without carotid calcification. Conclu-sion: IMT, years on hemodialysis and serum calcium phosphorus product were main influential factors of carotid calcification 'in MIlD and systolic/pulse blood pressure, higher CRP level, lower serum albumin were closely correlated with carotid calcification. Carotid calcification was very prevalent in MHD patients.