CAJ | 학술논문

目的探讨Asperger综合征(AS)儿童共患精神分裂症的比例并对相关因素进行分析,为AS的评估和干预提供可能的指导.方法对采用DSM-IV标准确诊为AS且定期复诊(至少每6个月1次或每年2次),并有详细完整记录的139名5～15岁患者进行回顾性调查分析.结果有5例AS患者共患精神分裂症,均为男性,年龄为10～14岁.共患精神分裂症组患者平均言语智商(VIQ)、操作智商(PIQ)、总智商(FIQ)分别为(96.3±15.0)分、(81.7±6.4)分、(88.3±8.0)分,非共患组VIQ、PIQ、FIQ分别为(91.8±20.8)分、(88.6±17.7)分、(89.5±18.9)分,2组间差异无显著性( P ＞0.01);共患组比非共患组有更高比例的一、二级亲属精神病家族史( P ＜0.01).结论 AS患者共患精神分裂症的比率较高,在临床治疗中应予重视.
목적 탐토Asperger종합정(AS)인동공환정신분렬증적비례병대상관인소진행분석,위AS적평고화간예제공가능적지도.방법 대채용DSM-IV표준학진위AS차정기복진(지소매6개월1차혹매년2차),병유상세완정기록적139명5～15세환자진행회고성조사분석.결과 유5례AS환자공환정신분렬증,균위남성,년령위10～14세.공환정신분렬증조환자평균언어지상(VIQ)、조작지상(PIQ)、총지상(FIQ)분별위(96.3±15.0)분、(81.7±6.4)분、(88.3±8.0)분,비공환조VIQ、PIQ、FIQ분별위(91.8±20.8)분、(88.6±17.7)분、(89.5±18.9)분,2조간차이무현저성( P ＞0.01);공환조비비공환조유경고비례적일、이급친속정신병가족사( P ＜0.01).결론 AS환자공환정신분렬증적비솔교고,재림상치료중응여중시.
Objective To study the rate of children with Asperger syndrome (AS) comorbid with schizophrenia and to analyse the related factors. Methods 139 detailed case records of patient (according to DSM-IV criteria ) aged 5.4 ～15.2 were selected for review,and the patients had received comprehensive evaluations and were followed periodically at our center( at least semiannually or twice per year). Results There were five male individuals had a diagnosis of schizophrenia when they aged 10.1～14.0. The average VIQ,PIQ,FIQ of individuals comorbid with schizophrenia were respectively 96.3±15.0,81.7±6.4,88.3±8.0 and outcomes of the rest individuals were respectively 91.8±20.8,88.6±17.7,89.5±18.9,there were no significant statistically difference between two groups( P ＞0.01). The frequency of psychiatric history of the first or the second family in the individuals comorbid with schizophrenia were higher than that in the individuals without schizophrenia( P ＜0.01).Conclusion It appears that the frequency of schizophrenia among AS patients is high,which should pay attention to.