CAJ | 학술논문

目的评价放疗联合顺铂综合治疗Ⅲ期宫颈癌疗效。方法同期对比分析经放疗加顺铂化疗87例和单纯经放疗70例Ⅲ期宫颈癌患者5年生存率、局部控制率、远处转移率和并发症。结果5年生存率：联合组59.0%，单放组41.4%。局部未控或复发率：联合组46.0%，单放组64.3%。远处转移率：联合组34.5%，单放组35.7%。放射性直肠炎：联合组4.90%，单放组5.71%。放射性膀胱炎：联合组4.60%，单放组4.30%。结论放射治疗联合顺铂化疗，提高局部控制率和5年生存率，远转率和并发症无差异。
목적평개방료연합순박종합치료Ⅲ기궁경암료효。방법동기대비분석경방료가순박화료87례화단순경방료70례Ⅲ기궁경암환자5년생존솔、국부공제솔、원처전이솔화병발증。결과5년생존솔：연합조59.0%，단방조41.4%。국부미공혹복발솔：연합조46.0%，단방조64.3%。원처전이솔：연합조34.5%，단방조35.7%。방사성직장염：연합조4.90%，단방조5.71%。방사성방광염：연합조4.60%，단방조4.30%。결론방사치료연합순박화료，제고국부공제솔화5년생존솔，원전솔화병발증무차이。
Objective To observe the clinical effects of combined cisplatinwith radiotherapy for stage Ⅲ cervical cancer.Methods 87 patients received concurrent cisplatin radiotherapy and adjuvant chemotherapy, and 70 patients received radiotherapy alone. Results 5 - year survival rate in radiotherapy plus cisplatin group and in radiotherapy alone group was 59.0 %and 41.4% respectively. Local failure rate was 46.0% and 64.3% respectively. Distant metastasis rate and adverse effects were similar. Conclusion Combined cisplatin with radiotherapy can elevate the local control rate and improve survival rate,but for the disease turning and complications there is no difference.