CAJ | 학술논문

目的：提高新生儿破伤风合并败血症的治愈率。方法：通过近5年对新生儿破伤风脐部感染的细菌学调查及耐药谱研究，尽早在抗破伤风细菌感染的同时，联合应用高效、广谱、低毒的抗生素。结果：以第3代头孢菌素为首选的经验用药方案，对提高治愈率有明显疗效。结论：新生儿破伤风合并败血症的频率高，如果单纯抗破伤风外毒素治疗，而忽视经脐部感染的其它细菌所致的败血症治疗时，新生儿存活率仍低。因此预先估计到有败血症存在的可能，及时用药，是治疗成功的关键。
목적：제고신생인파상풍합병패혈증적치유솔。방법：통과근5년대신생인파상풍제부감염적세균학조사급내약보연구，진조재항파상풍세균감염적동시，연합응용고효、엄보、저독적항생소。결과：이제3대두포균소위수선적경험용약방안，대제고치유솔유명현료효。결론：신생인파상풍합병패혈증적빈솔고，여과단순항파상풍외독소치료，이홀시경제부감염적기타세균소치적패혈증치료시，신생인존활솔잉저。인차예선고계도유패혈증존재적가능，급시용약，시치료성공적관건。
Objective:To explore and improve the cure rate of tetanus neonatorum combined with other pathogenic septicemia.Methods:To retrospectively research the last five years of bacteriological investigation and drug resistant/drug-sensitivity test onsamples from blood and omphalitis who suffered from tetanus neonatorum. Combined application of effective,broad spectrum and lowtoxic antibiotic in the same times of treating infection of hacillus tetani as early as possible. Results: Using the third generation ofcephalothin as poior selection as experimental treatment has shown remarkable effect in increasing the cure rate. Conclusions :There isa high morbility in tetanus neonatarum combind with septicemia causce by other bate rial pathogen. The survival rate would be low ifone stress simplyon treating tatenus neonatorum while overlooking the possibility of other bacterial infection through ambilical cordwhich may cause septicemia simutaneously. The key to success in treating tetanus neonatorum is one must have the seace to estimatethat tetanus neonatorum has the high posibility of complex infection and choose an right treatment scheme on time.