CAJ | 학술논문

目的：观察不同剂量稀土元素-镧对大鼠睾丸7型水通道(aquaporin 7， AQP 7)基因表达水平的影响。方法：取硝酸镧［La(NO3)3］灌胃6个月大鼠的睾丸组织提取总RNA进行Northern blot 分析。结果：低剂量La(NO3)3（0.1 mg/kg）抑制大鼠睾丸AQP 7的mRNA表达，而高剂量La(NO3)3 (20 mg/kg) 的作用与对照组比较无明显差别。结论：大鼠睾丸内可见AQP 7mRNA的表达；硝酸镧能影响大鼠睾丸AQP 7 mRNA表达的强度。
목적：관찰불동제량희토원소-란대대서고환7형수통도(aquaporin 7， AQP 7)기인표체수평적영향。방법：취초산란［La(NO3)3］관위6개월대서적고환조직제취총RNA진행Northern blot 분석。결과：저제량La(NO3)3（0.1 mg/kg）억제대서고환AQP 7적mRNA표체，이고제량La(NO3)3 (20 mg/kg) 적작용여대조조비교무명현차별。결론：대서고환내가견AQP 7mRNA적표체；초산란능영향대서고환AQP 7 mRNA표체적강도。
AIM: To find out whether different dosage of rare earth element-lanthanum can influence the expression of aquaporin 7(AQP 7) in the testis of rats. METHODS:Rats were fed with lanthanum nitrate ［La(NO3)3］ and killed 6 months later. Testes were then removed immediately to extract total RNA. Northern blot analysis is performed finally. RESULTS:0.1 mg/kg La(NO3)3 depressed the expression of AQP 7 in rat testis, while 20 mg/kg La(NO3)3 had no significant effect on it. CONCLUSION: AQP 7 expession is found in the rat testis; La(NO3)3 can depress the expression of AQP 7 in the rat testis.