CAJ | 학술논문

目的：探讨苍白球腹后部毁损术(PVP)治疗帕金森病(PD)的手术方法及疗效。方法：采用坐标定位结合MRI图象定位，在微电极导向下，完成对6例病人单侧苍白球腹后部(Gpi)的定位，并实施毁损。结果： 6例患者的震颤、僵硬及运动迟缓均得到明显改善， UPDRS运动部分积分下降，无永久并发症。结论：坐标结合MRI图象法能准确定位Gpi，微电极记录是其必要的补充， PVP能全面改善PD患者的症状，是一种安全有效的方法。
목적：탐토창백구복후부훼손술(PVP)치료파금삼병(PD)적수술방법급료효。방법：채용좌표정위결합MRI도상정위，재미전겁도향하，완성대6례병인단측창백구복후부(Gpi)적정위，병실시훼손。결과： 6례환자적진전、강경급운동지완균득도명현개선， UPDRS운동부분적분하강，무영구병발증。결론：좌표결합MRI도상법능준학정위Gpi，미전겁기록시기필요적보충， PVP능전면개선PD환자적증상，시일충안전유효적방법。
Objective： To probe the effects and methods of microelectrod stereotatic guided PVP. Methods: With the help of microelectrod stereotatic guided, combined the coordinates and MRI films, 6 pateients of PD was perfomed ipsilateral PVP. Results: Tremor, rigidity and bradykinesia of all patients are improved significantly. Postoperatiion UPDRW score are decreased. No permanent operatve complications.Conclusion: The initial target can be determined by combination the coordinates and MRI films. Microelectrod recording provides important targeting information, The PVP is a safe and effective operation for PD.