CAJ | 학술논문

目的：观察具有益心气、通心窍作用的复方——养心健脑方治疗阿尔茨海默病(AD)的临床疗效，并与西药脑复康对照组比较。方法：选择DSM-ⅢR、HDS、ADL、CRBRS等国际流行量表进行诊断，对智力、日常生活能力、认知功能及精神行为方面作疗效评估。疗程3个月。结果：养心健脑方对AD患者的智力、日常生活能力、多项认知功能均有不同程度的改善，明显优于脑复康，其中养心健脑方对AD患者的智力总有效率为78.79％，对日常生活能力总有效率为57.58％，对定向力总有效率为66.67％，对远期记忆总有效率为60.61％，对常识能力总有效率为39.39％，两组相比有显著性差异(P＜0.005)。而计算力、近记忆力、理解交谈能力、神情等方面虽有不同程度的改善，但两组相比无显著差异。结论：养心健脑方对AD的智力、日常生活能力和认知功能中的定向力、远期记忆、常识，以及社交能力中的合作力有明显的改善作用。尤其值得注意的是对其核心症状——智力减退和记忆障碍有明显作用。
목적：관찰구유익심기、통심규작용적복방——양심건뇌방치료아이자해묵병(AD)적림상료효，병여서약뇌복강대조조비교。방법：선택DSM-ⅢR、HDS、ADL、CRBRS등국제류행량표진행진단，대지력、일상생활능력、인지공능급정신행위방면작료효평고。료정3개월。결과：양심건뇌방대AD환자적지력、일상생활능력、다항인지공능균유불동정도적개선，명현우우뇌복강，기중양심건뇌방대AD환자적지력총유효솔위78.79％，대일상생활능력총유효솔위57.58％，대정향력총유효솔위66.67％，대원기기억총유효솔위60.61％，대상식능력총유효솔위39.39％，량조상비유현저성차이(P＜0.005)。이계산력、근기억력、리해교담능력、신정등방면수유불동정도적개선，단량조상비무현저차이。결론：양심건뇌방대AD적지력、일상생활능력화인지공능중적정향력、원기기억、상식，이급사교능력중적합작력유명현적개선작용。우기치득주의적시대기핵심증상——지력감퇴화기억장애유명현작용。
Thirty-three cases of Alzheimer's dementia(AD)were treated with Heart and Brain Benefiting For-mula (HBBF). These were selected in accordance with DSM-Ⅲ R,HDS,ADL and CRBRS. The therapeutic effectswere judged according to ability to deal with daily life ,cognition functions and ability to social activity. Fifteen caseswere treated with piracetam for 3 months as control group. The results showed that the effects of HBBF were bet-ter as compared with piracetam. Total effective rates of HBBF were 78. 79％ in intelligence, 57.58％ in ability todeal with daily life, 66. 67％ in ability to orientation, 60. 61％ in remote memory, 39.39％ in general knowl-edge. There were remarkable differenecs between the two groups. HBBF was beneficial to abilities of calculation,recent memory ,understanding and talking ,and psychiatric symptoms ,whereas there was no statistical differencescompared with control group.