CAJ | 학술논문

胰岛移植具有创伤小、风险低、可阻止或延缓慢性并发症、有望根治糖尿病等优点,但是胰岛的分离、纯化及移植技术含量高,导致胰岛的回收率仍然较低;另外,供体短缺、移植后移植物及其功能的维持、免疫排斥反应等限制了胰岛移植在临床的广泛应用.
이도이식구유창상소、풍험저、가조지혹연완만성병발증、유망근치당뇨병등우점,단시이도적분리、순화급이식기술함량고,도치이도적회수솔잉연교저;령외,공체단결、이식후이식물급기공능적유지、면역배척반응등한제료이도이식재림상적엄범응용.
Clinical islet transplantation is currently being explored as a treatment for its superiorities of lesser in vasive,lower risk,avoiding or preventing chronic complications.Because of the difficulty in isolation,purification and transplantation,the yield of islet is lower than needed;shortage of donor,difficulty in obtaining adequate islet cells for sustaining B cell mass and function over time,and immune rejection reactions are the hurdels to widespread application of islet transplantation.