中华行为医学与脑科学杂志
中華行為醫學與腦科學雜誌
중화행위의학여뇌과학잡지
CHINESE JOURNAL OF BEHAVIORAL MEDICINE AND BRAIN SCIENCE
2009年
11期
985-987
,共3页
肖琳%郭宗君%周晋%魏华%王晓林%邢昂
肖琳%郭宗君%週晉%魏華%王曉林%邢昂
초림%곽종군%주진%위화%왕효림%형앙
脑血管病%再认记忆%不同部位
腦血管病%再認記憶%不同部位
뇌혈관병%재인기억%불동부위
Cerebrovascular disease%Recognition memory%Different areas
目的 探讨脑血管病不同部位损伤对再认记忆的影响.方法 脑血管病组(共70例,按损伤脑区不同分为基底节区损伤组、额叶损伤组、颞叶损伤组,按损伤灰质、白质不同可分为皮层损伤组、皮层下损伤组,按损伤不同半球分为左半球损伤组、右半球损伤组)与对照组(共75例)在微机上完成双字词及无意义图形再认两项测验,观察脑血管病不同部位损伤患者再认成绩的差异及脑血管病组与对照组再认成绩的差异.结果 脑血管病组双字词及无意义图形再认测验成绩[(10.13±2.72)分,(9.50±3.02)分]均显著低于正常对照组[(12.96±2.97)分,(13.35±2.56)分](t值分别为5.98和8.30,均P<0.01),皮层损伤组[(9.08±2.11)分,(8.26±2.72)分]低于皮层下损伤组[(11.38±2.86)分,(10.97±2.72)分](t值分别为3.86和4.15,均P<0.01);左半球损伤组双字词再认成绩[(9.33±2.61)分]显著低于右半球损伤组[(10.84±2.65)分](t=2.39,P<0.05);基底节区损伤组、额叶损伤组、颞叶损伤组3组比较,2项测验成绩差异均有显著性(F值分别为10.00和11.64,均P<0.01);颞叶损伤组两项再认测验成绩[(8.30±2.08)分,(7.35±2.83)分]均显著低于基底节区[(11.38±2.86)分,(10.97±2.72)分]及额叶损伤组[(9.94±1.83)分,(9.28±2.24)分](P<0.01,P<0.05),额叶损伤组2项测验成绩[(9.94±1.83)分,(9.28±2.24)分]均显著低于基底节区损伤组[(11.38±2.86)分,(10.97±2.72)分,均P<0.05].结论 脑血管病不同部位损伤患者有明显再认记忆障碍,皮层损伤组较皮层下损伤组再认记忆障碍严重,颞叶损伤组再认记忆障碍最重.
目的 探討腦血管病不同部位損傷對再認記憶的影響.方法 腦血管病組(共70例,按損傷腦區不同分為基底節區損傷組、額葉損傷組、顳葉損傷組,按損傷灰質、白質不同可分為皮層損傷組、皮層下損傷組,按損傷不同半毬分為左半毬損傷組、右半毬損傷組)與對照組(共75例)在微機上完成雙字詞及無意義圖形再認兩項測驗,觀察腦血管病不同部位損傷患者再認成績的差異及腦血管病組與對照組再認成績的差異.結果 腦血管病組雙字詞及無意義圖形再認測驗成績[(10.13±2.72)分,(9.50±3.02)分]均顯著低于正常對照組[(12.96±2.97)分,(13.35±2.56)分](t值分彆為5.98和8.30,均P<0.01),皮層損傷組[(9.08±2.11)分,(8.26±2.72)分]低于皮層下損傷組[(11.38±2.86)分,(10.97±2.72)分](t值分彆為3.86和4.15,均P<0.01);左半毬損傷組雙字詞再認成績[(9.33±2.61)分]顯著低于右半毬損傷組[(10.84±2.65)分](t=2.39,P<0.05);基底節區損傷組、額葉損傷組、顳葉損傷組3組比較,2項測驗成績差異均有顯著性(F值分彆為10.00和11.64,均P<0.01);顳葉損傷組兩項再認測驗成績[(8.30±2.08)分,(7.35±2.83)分]均顯著低于基底節區[(11.38±2.86)分,(10.97±2.72)分]及額葉損傷組[(9.94±1.83)分,(9.28±2.24)分](P<0.01,P<0.05),額葉損傷組2項測驗成績[(9.94±1.83)分,(9.28±2.24)分]均顯著低于基底節區損傷組[(11.38±2.86)分,(10.97±2.72)分,均P<0.05].結論 腦血管病不同部位損傷患者有明顯再認記憶障礙,皮層損傷組較皮層下損傷組再認記憶障礙嚴重,顳葉損傷組再認記憶障礙最重.
목적 탐토뇌혈관병불동부위손상대재인기억적영향.방법 뇌혈관병조(공70례,안손상뇌구불동분위기저절구손상조、액협손상조、섭협손상조,안손상회질、백질불동가분위피층손상조、피층하손상조,안손상불동반구분위좌반구손상조、우반구손상조)여대조조(공75례)재미궤상완성쌍자사급무의의도형재인량항측험,관찰뇌혈관병불동부위손상환자재인성적적차이급뇌혈관병조여대조조재인성적적차이.결과 뇌혈관병조쌍자사급무의의도형재인측험성적[(10.13±2.72)분,(9.50±3.02)분]균현저저우정상대조조[(12.96±2.97)분,(13.35±2.56)분](t치분별위5.98화8.30,균P<0.01),피층손상조[(9.08±2.11)분,(8.26±2.72)분]저우피층하손상조[(11.38±2.86)분,(10.97±2.72)분](t치분별위3.86화4.15,균P<0.01);좌반구손상조쌍자사재인성적[(9.33±2.61)분]현저저우우반구손상조[(10.84±2.65)분](t=2.39,P<0.05);기저절구손상조、액협손상조、섭협손상조3조비교,2항측험성적차이균유현저성(F치분별위10.00화11.64,균P<0.01);섭협손상조량항재인측험성적[(8.30±2.08)분,(7.35±2.83)분]균현저저우기저절구[(11.38±2.86)분,(10.97±2.72)분]급액협손상조[(9.94±1.83)분,(9.28±2.24)분](P<0.01,P<0.05),액협손상조2항측험성적[(9.94±1.83)분,(9.28±2.24)분]균현저저우기저절구손상조[(11.38±2.86)분,(10.97±2.72)분,균P<0.05].결론 뇌혈관병불동부위손상환자유명현재인기억장애,피층손상조교피층하손상조재인기억장애엄중,섭협손상조재인기억장애최중.
Objective To study the recognition in patients with cerebrovascular disease in different areas. Methods The recognitive tests including Chinese words recognizing test and nonsense pictures recognizing test were accomplished in computer, and the differences of recognitive functions between patients with cerebrovascular disease (70 cases, they divided into basal ganglia damaged group, frontal lobe damaged group and temporal lobe damaged group according to damaged brain areas;divided into cortex group and under cortex group according to damaged gray matter or white matter;divided into left and right hemisphere groups according to different damaged hemispheres) and normal controls(75 cases) were compared. The scores of patients with cerebrovascular disease in different cerebral areas were compared too. Results The two scores of the Chinese words recognizing test and nonsense pictures recognizing test in patients with cerebrovascular disease (10.13±2.72,9.50 ±3.02) were significantly lower than that in normal controls( 12.96 ±2.97,13.35 ±2.56) ( t_1 = 5.98, t_2=8.30, both P<0.01) , and in patients with cerebrovascular disease focuses in cortex (9.08 ±2. 11, 8.26 ±2.72)were lower than that in patients with cerebrovascular disease focuses in under cortex(11.38 ±2.86, 10.97 ±2.72) (t_1 = 3.86, t_2=4. 15, both P<0.01) ;the scores of Chinese characters recognizing test in patients with left hemisphere lesion(9. 33 ± 2.61) was lower than that in patients with right hemisphere lesion( 10. 84 ± 2.65 ) ( t ,= 2. 39, P < 0. 05 ). The scores of all tests in patients with cerebrovascular disease focuses in basal ganglia,frontal lobe and temporal lobe were significantly different(F_1 =10.00, F_2 = 11.64, both P<0.01). The scores of the two tests in patients with cerebrovascular disease focuses in temporal lobe(8. 30 ± 2.08, 7. 35 ± 2. 83 ) were lower than that in patients with cerebrovascular disease focuses in basal ganglia(11. 38 ± 2. 86, 10.97 ±2.72) and frontal lobe(9. 94 ± 1. 83, 9.28 ±2.24) (P<0.01, P<0.05) ;the scores of the two tests in patients with cerebrovascular disease focuses in frontal lobe(9.94 ± 1. 83, 9.28 ± 2. 24) were lower than that in patients with cerebrovascular disease focuses in basal ganglia(11. 38 ±2.86, 10.97 ±2.72) (P<0.05). Conclution The disturbances of recognition were observed in patients with cerebrovascular disease. The disturbances of recognition in patients with cerebrovascular dis-ease focuses in cortex were more serious than that in patients with cerebrovascular focuses in under cortex;the disturbances in patients with temporal lobe lesion were most serious.