中华小儿外科杂志
中華小兒外科雜誌
중화소인외과잡지
CHINESE JOURNAL OF PEDIATRIC SURGERY
2009年
7期
432-434
,共3页
烧伤%生物敷料%细菌感染
燒傷%生物敷料%細菌感染
소상%생물부료%세균감염
Burns%Biological dressings%Bacterial infections
目的 观察浸浴结合人工生物敷料和血小板胶治疗烧伤后期残余创面的效果.方法 将有烧伤后期残余创面的56例患儿分为实验组(28例)和对照组(28例).实验组患儿浸浴后,用血小板胶喷洒于创面,将生物敷料覆盖于创面行半暴露疗法,用血小板胶喷湿敷料2次/d,每2至3 d浸浴1次并更换敷料;对照组创面消毒后仅以单层碘伏纱布覆盖行半暴露疗法.1个疗程(10 d)结束后,比较二组患儿的治愈率、有效率、创面细菌学情况及相关安全性指标.结果 实验组和对照组患儿的治愈率、有效率、细菌清除率分别为64.3%、89.3%、92.3%和32.1%、67.9%、72.0%,二组上述指标比较,差异均有统计学意义(P<0.01).二组患儿未发生不良反应.结论 浸浴结合应用新型人工生物敷料和血小板胶治疗烧伤患儿后期残余创面安全、有效,可控制创面感染、提高治愈率.
目的 觀察浸浴結閤人工生物敷料和血小闆膠治療燒傷後期殘餘創麵的效果.方法 將有燒傷後期殘餘創麵的56例患兒分為實驗組(28例)和對照組(28例).實驗組患兒浸浴後,用血小闆膠噴灑于創麵,將生物敷料覆蓋于創麵行半暴露療法,用血小闆膠噴濕敷料2次/d,每2至3 d浸浴1次併更換敷料;對照組創麵消毒後僅以單層碘伏紗佈覆蓋行半暴露療法.1箇療程(10 d)結束後,比較二組患兒的治愈率、有效率、創麵細菌學情況及相關安全性指標.結果 實驗組和對照組患兒的治愈率、有效率、細菌清除率分彆為64.3%、89.3%、92.3%和32.1%、67.9%、72.0%,二組上述指標比較,差異均有統計學意義(P<0.01).二組患兒未髮生不良反應.結論 浸浴結閤應用新型人工生物敷料和血小闆膠治療燒傷患兒後期殘餘創麵安全、有效,可控製創麵感染、提高治愈率.
목적 관찰침욕결합인공생물부료화혈소판효치료소상후기잔여창면적효과.방법 장유소상후기잔여창면적56례환인분위실험조(28례)화대조조(28례).실험조환인침욕후,용혈소판효분쇄우창면,장생물부료복개우창면행반폭로요법,용혈소판효분습부료2차/d,매2지3 d침욕1차병경환부료;대조조창면소독후부이단층전복사포복개행반폭로요법.1개료정(10 d)결속후,비교이조환인적치유솔、유효솔、창면세균학정황급상관안전성지표.결과 실험조화대조조환인적치유솔、유효솔、세균청제솔분별위64.3%、89.3%、92.3%화32.1%、67.9%、72.0%,이조상술지표비교,차이균유통계학의의(P<0.01).이조환인미발생불량반응.결론 침욕결합응용신형인공생물부료화혈소판효치료소상환인후기잔여창면안전、유효,가공제창면감염、제고치유솔.
Objective To observe the residual burn wounds of children treated with artificial dermis and antologous platelet gel (APG) after immersion bath at late post-burn stage. Methods Fif-ty-six children with residual wounds at late post-burn stage were enrolled in the study and randomly al-located into A(n = 28,experimental) and B(n = 28, control) groups. After treatment with immersion bath, the wounds in group A were treated with semi-exposure method. The wounds were covered with artificial dermis in suitable shape and spray APG twice a day, the artificial dermis was changed every 2 day or every 3 days after immersion bath. To compare the treatment effect, the wounds in group B were only treated with a dressing of monolayer gauze wetted with povidone iodine. The clinical out-comes, bacteriological findings and associated safety parameters were compared between two groups on 10 days after treatment. Results The wound healing rate, efficacy and the bacterial clearance rate in A group were 64.3% ,89.3% and 92.3%, respectively, and they were significantly higher than those in B group(32.1%, 67.9% and 72.0%, respectively, P<0.01). No adverse side-effect was noted in ei-ther group. Conclusions Application of artificial dermis and APG after immersion bath is safe and ef-fective for the elimination of residual wounds at late post-burn stage, which is beneficial to control wound infection and promote the wound healing.
