现代肿瘤医学
現代腫瘤醫學
현대종류의학
JOURNAL OF MODERN ONCOLOGY
2009年
8期
1520-1521
,共2页
古伟光%谢忠%廖思海%罗海涛
古偉光%謝忠%廖思海%囉海濤
고위광%사충%료사해%라해도
胆管癌%吉西他滨%草酸铂%联合化疗
膽管癌%吉西他濱%草痠鉑%聯閤化療
담관암%길서타빈%초산박%연합화료
cholangiocarcinoma%gemcitabine%oxaliplatin%combined chemotherapy
目的:观察吉西他滨联合草酸铂治疗晚期肝外胆管癌的近期疗效.方法:30例晚期胆管癌患者采用化疗:吉西他滨1000mg/m2,静脉滴注30-60分钟,第1,8天给药;草酸铂100mg/m2,静脉滴注2小时,第2天.21天为一个周期.结果:30例中无1例达完全缓解,部分缓解6例(20%),稳定11例(36.7%).14例(46.7% )患者疼痛得到缓解,生活质量提高.结论:吉西他滨联合草酸铂治疗晚期无法手术的肝外胆管癌具有较好的近期疗效且不良反应可以耐受.
目的:觀察吉西他濱聯閤草痠鉑治療晚期肝外膽管癌的近期療效.方法:30例晚期膽管癌患者採用化療:吉西他濱1000mg/m2,靜脈滴註30-60分鐘,第1,8天給藥;草痠鉑100mg/m2,靜脈滴註2小時,第2天.21天為一箇週期.結果:30例中無1例達完全緩解,部分緩解6例(20%),穩定11例(36.7%).14例(46.7% )患者疼痛得到緩解,生活質量提高.結論:吉西他濱聯閤草痠鉑治療晚期無法手術的肝外膽管癌具有較好的近期療效且不良反應可以耐受.
목적:관찰길서타빈연합초산박치료만기간외담관암적근기료효.방법:30례만기담관암환자채용화료:길서타빈1000mg/m2,정맥적주30-60분종,제1,8천급약;초산박100mg/m2,정맥적주2소시,제2천.21천위일개주기.결과:30례중무1례체완전완해,부분완해6례(20%),은정11례(36.7%).14례(46.7% )환자동통득도완해,생활질량제고.결론:길서타빈연합초산박치료만기무법수술적간외담관암구유교호적근기료효차불량반응가이내수.
Objective:To observe the therapeutic effect of gemcitabine combined with oxaliplatin for the treatment of advanced cholangiocarcinoma.Methods:Thirty patients were given gemcitabine and oxaliplatin intravenously.Results:There was no complete response.The partial response rate was 20% and SD 36.7%,14 patients (46.7%) had relie of pain and improvement in quality of life.The toxicity was low and tolerable.Conclusion:Gemcitabine combined with oxaliplatin is an effective and safe regimen for treating advanced cholangiocarcinoma.
