CAJ | 학술논문

目的:探讨喉白斑病的临床及病理特征,降低癌变率.方法:临床诊断并经病理证实的74例喉白斑病患者接受显微支撑喉镜下声带白斑切除术或声带白斑激光切除术,术后随访1～4年.结果:18例单纯白斑患者术后无一例复发;56例白斑伴不典型增生患者术后7例仍声嘶;3例复发,并相继进行2次或多次手术;3例癌变.结论:①手术是治疗喉白斑病的主要手段,且效果较好.②喉白斑病伴轻、中、重度非典型增生者都有较高的癌变率,需要引起高度重视,在早期病变时,如患者同意,也可适当扩大手术范围,以防复发或癌变.③手术后患者的密切随访至关重要.
목적:탐토후백반병적림상급병리특정,강저암변솔.방법:림상진단병경병리증실적74례후백반병환자접수현미지탱후경하성대백반절제술혹성대백반격광절제술,술후수방1～4년.결과:18례단순백반환자술후무일례복발;56례백반반불전형증생환자술후7례잉성시;3례복발,병상계진행2차혹다차수술;3례암변.결론:①수술시치료후백반병적주요수단,차효과교호.②후백반병반경、중、중도비전형증생자도유교고적암변솔,수요인기고도중시,재조기병변시,여환자동의,야가괄당확대수술범위,이방복발혹암변.③수술후환자적밀절수방지관중요.
Objective: To study the clinic and pathological features of leukoplakia of the larynx, and reduce canceration rate. Method: Seventy-four postoperative patients of leukoplakia of the larynx were followed up for four years by telephone or clinic service. Result: None of eighteen cases of pure leukoplakia was recurrence. Fifty-six ca-ses were leukoplakia with epithelial dysplasia histologically. Seven out of fifty-six postoperative cases occurred hoarseness; three out of fifty-six postoperative cases recured, and accepted twice or more operations successively; three out of fifty-six postoperative cases occurred canceration. Conclusion:Operation is the main means for the treatment of leukoplakia of the larynx, and the effect is comparatively well. The patients with histological epitheli-al dysplasia should be pay great attention because of their higher canceration rate, and enlarged operation ranges appropriately with the patient consent could effectually prevent recurrence or canceration during the early lesions. Close observation is important for these patients.