中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2010年
2期
160-161
,共2页
甲状腺功能亢进症%妊娠结局
甲狀腺功能亢進癥%妊娠結跼
갑상선공능항진증%임신결국
Hyperthyroidism%Pregnancy outcome
目的 探讨妊娠期甲状腺功能亢进对妊娠结局的影响.方法 回顾性分析80例妊娠合并甲状腺功能亢进症患者(甲亢组)的临床资料,按照妊娠期治疗是否规范分为治疗组(61例)及未治组(19例);同时按照1:2比例随机选择160例健康妊娠妇女为对照组.比较三组间分娩情况、母体及围生儿结局等差异.结果 甲亢组妊娠高血压疾病发病率10.0%、心力衰竭发生率3.8%、剖宫产率61.4%、早产发生率7.6%、窒息发生率7.6%、甲状腺功能低下发生率3.8%、病死率3.8%,与对照组的1.3%、41.3%、1.3%、0.6%、0、0相比较,差异均有统计学意义(均P＜0.05),两组新生儿畸形发生率无差异(P＞0.05);治疗组妊娠高血压疾病、心力衰竭、早产、窒息等发生率分别为3.3%、3.3%、3.3%、0,病死率0,与未治组的31.6%、15.8%、21.1%、15.8%、10.5%相比较,差异均有统计学意义(均P＜0.05),而两组甲状腺功能低下发生率、剖宫产率、畸形发生率等差异无统计学意义.结论 甲状腺功能亢进可增加妊娠并发症的发生率,规范治疗可改善妊娠结局.
目的 探討妊娠期甲狀腺功能亢進對妊娠結跼的影響.方法 迴顧性分析80例妊娠閤併甲狀腺功能亢進癥患者(甲亢組)的臨床資料,按照妊娠期治療是否規範分為治療組(61例)及未治組(19例);同時按照1:2比例隨機選擇160例健康妊娠婦女為對照組.比較三組間分娩情況、母體及圍生兒結跼等差異.結果 甲亢組妊娠高血壓疾病髮病率10.0%、心力衰竭髮生率3.8%、剖宮產率61.4%、早產髮生率7.6%、窒息髮生率7.6%、甲狀腺功能低下髮生率3.8%、病死率3.8%,與對照組的1.3%、41.3%、1.3%、0.6%、0、0相比較,差異均有統計學意義(均P＜0.05),兩組新生兒畸形髮生率無差異(P＞0.05);治療組妊娠高血壓疾病、心力衰竭、早產、窒息等髮生率分彆為3.3%、3.3%、3.3%、0,病死率0,與未治組的31.6%、15.8%、21.1%、15.8%、10.5%相比較,差異均有統計學意義(均P＜0.05),而兩組甲狀腺功能低下髮生率、剖宮產率、畸形髮生率等差異無統計學意義.結論 甲狀腺功能亢進可增加妊娠併髮癥的髮生率,規範治療可改善妊娠結跼.
목적 탐토임신기갑상선공능항진대임신결국적영향.방법 회고성분석80례임신합병갑상선공능항진증환자(갑항조)적림상자료,안조임신기치료시부규범분위치료조(61례)급미치조(19례);동시안조1:2비례수궤선택160례건강임신부녀위대조조.비교삼조간분면정황、모체급위생인결국등차이.결과 갑항조임신고혈압질병발병솔10.0%、심력쇠갈발생솔3.8%、부궁산솔61.4%、조산발생솔7.6%、질식발생솔7.6%、갑상선공능저하발생솔3.8%、병사솔3.8%,여대조조적1.3%、41.3%、1.3%、0.6%、0、0상비교,차이균유통계학의의(균P＜0.05),량조신생인기형발생솔무차이(P＞0.05);치료조임신고혈압질병、심력쇠갈、조산、질식등발생솔분별위3.3%、3.3%、3.3%、0,병사솔0,여미치조적31.6%、15.8%、21.1%、15.8%、10.5%상비교,차이균유통계학의의(균P＜0.05),이량조갑상선공능저하발생솔、부궁산솔、기형발생솔등차이무통계학의의.결론 갑상선공능항진가증가임신병발증적발생솔,규범치료가개선임신결국.
Objective To discuss the impact of hyperthyroidism on pregnancy outcome.Methods Clinical data of 80 pregnancy patients with hyperthyroidism(hyperthyroidism group)were retrospectively analyzed,in accordance with the norms of treatment during pregnancy is divided into treatment group(61 cases)and untreated group(19 cases);At the same time,in accordance with the ratio of 1:2 160 cases of healthy pregnant women were randomly selected as control group.childbirth,the maternal and perinatal outcome in three groups were compared.Results Graves disease group the incidence of pregnancy-induced hypertension 10.0%,3.8% incidence of heart failure,cesarean section rate of 61.4%,7.6% incidence of prematurity,asphyxia incidence of 7.6%,a low incidence of 3.8%,the mortality rate 3.8%,and 1.3% of the control group,41.3%,1.3%,0.6%,0,0,the differences were statistically significant(P＜0.05),the incidence of neonatal abnormalities in two groups is not different(P＞0.05);the treatment group of diseases of pregnancy-induced hypertension,heart failure,premature birth,asphyxia,such as the incidence were 3.3%,3.3%,3.3%,0,0 mortality,with non-governing group of 31.6%,15.8%,21.1%,15.8%,10.5%.The differences were statistically significant(P＜0.05),and a low incidence of the two groups,the cesarean section rate,incidence of deformities such as no difference.Conclusion Hyperthyroidism can increase the incidence of pregnancy complications,and standardize the treatment can improve pregnancy outcome.
