CAJ | 학술논문

目的调查江苏省老年人慢性肾脏病(CKD)的患病率及危险因素.方法采用分层随机抽样方法,对江苏省两个地区1404名60岁及以上常住居民进行问卷调查、肾损伤指标及相关危险因素的检测.结果 1316例资料完整的受访者中,CKD患病率为32.3%.Logistic回归分析显示年龄、性别、高血压、高胆固醇血症及高尿酸血症与CKD患病独立相关.当收缩压(SBP)为140～159 mm Hg、160～179 mm Hg、≥180 mm Hg时,SBP对应CKD的优势比(OR)值分别为0.675、1.330、1.416.当空腹血糖(FBG)为5.6～6.9 mmol/L和≥7.0 mmol/L时,FBG对应CKD的OR值分别为0.628和1.941.结论我国江苏地区老年人群CKD患病率较高,危险因素包括年龄、性别、高血压、高胆固醇血症及高尿酸血症,与发达国家相似.
목적 조사강소성노년인만성신장병(CKD)적환병솔급위험인소.방법 채용분층수궤추양방법,대강소성량개지구1404명60세급이상상주거민진행문권조사、신손상지표급상관위험인소적검측.결과 1316례자료완정적수방자중,CKD환병솔위32.3%.Logistic회귀분석현시년령、성별、고혈압、고담고순혈증급고뇨산혈증여CKD환병독립상관.당수축압(SBP)위140～159 mm Hg、160～179 mm Hg、≥180 mm Hg시,SBP대응CKD적우세비(OR)치분별위0.675、1.330、1.416.당공복혈당(FBG)위5.6～6.9 mmol/L화≥7.0 mmol/L시,FBG대응CKD적OR치분별위0.628화1.941.결론 아국강소지구노년인군CKD환병솔교고,위험인소포괄년령、성별、고혈압、고담고순혈증급고뇨산혈증,여발체국가상사.
Objective To survey the epidemiology of chronic kidney disease (CKD) among elderly people in two districts of Jiangsu province, China. Methods A total of 1404 residents aged 60 years or older in Huaian and Suzhou city in Jiangsu province were randomly recruited from the community population. All the people were screened for albuminuria (increased morning spot urine albumin-to-creatinine ratio, UACR) and reduced renal function (decreased eGFR by simplified MDRD equation). Urinary creatinine and albumin, serum creatinine, uric acid, cholesterol,triglyceride, low density lipoprotein-cholesterol, high-density lipoprotein cholesterol and fasting blood (1.73 m2) -1] and/or albuminuria (UACR ≥30 mg/g). The associations between healthy characteristics and indicators of kidney damage were examined. Results A total of 1316 (93.7%) elderly people completed the study. The prevalence of CKD was 32.3% and the awareness rate was only 9.6%. Albuminuria and reduced renal function were found in 30.2% and 3.2% of subjects respectively. The Logistic regression model showed that age, gender, hypertension,hypercholesterinemia and hyperuricaemia were independently associated with CKD. Systolic blood pressure (SBP) of 140-159 mm Hg exhibited a lower adjusted OR value (0.675) for CKD, while SBP of 160-179 mm Hg and of at least 180 mm Hg exhibited higher adjusted OR values (1.330 and 1.146). Similarly, FBG of 5.6-6.9 mmol/L exhibited a lower adjusted OR value for CKD as compared to FBG of at least 7.0 mmol/L (0.628 vs 1.941). Conclusions The prevalence of CKD in elderly people of Jiangsu province is quite high. Age, gender, hypertension,hypercholesterinemia and hyperuricaemia are independent risk factors for the development of CKD.