中成药
中成藥
중성약
CHINESE TRADITIONAL PATENT MEDICINE
2010年
1期
75-79
,共5页
刘法锦%孙冬梅%鲁佳慧%胥爱丽
劉法錦%孫鼕梅%魯佳慧%胥愛麗
류법금%손동매%로가혜%서애려
黄连%吴茱萸%薄层扣描法%盐酸小檗碱%盐酸巴马汀%盐酸药根碱
黃連%吳茱萸%薄層釦描法%鹽痠小檗堿%鹽痠巴馬汀%鹽痠藥根堿
황련%오수유%박층구묘법%염산소벽감%염산파마정%염산약근감
Rhizoma Coptidis%Fructus Evodiae%TLCS%berberine hydrochloride%palmatine hydrochloride%jatrorrhizine hydrochloride
目的:比较黄连中主要生物碱成分在黄连-吴茱萸药对配伍前后的差异.方法:采用TLCS法对黄连单煎液、黄连吴茱萸合煎液、黄连吴茱萸单煎混合液中盐酸小檗碱、盐酸巴马汀、盐酸药根碱的含量进行测定.结果:黄连与吴茱萸配伍后,盐酸小檗碱、盐酸巴马汀、盐酸药根碱的含量均显著降低,以盐酸小檗碱的减少较为明显.结论:两药合用,黄连生物碱含量均有不同程度降低,说明吴茱萸可制约黄连苦寒之性,为临床两药配伍使用提供了实验依据.
目的:比較黃連中主要生物堿成分在黃連-吳茱萸藥對配伍前後的差異.方法:採用TLCS法對黃連單煎液、黃連吳茱萸閤煎液、黃連吳茱萸單煎混閤液中鹽痠小檗堿、鹽痠巴馬汀、鹽痠藥根堿的含量進行測定.結果:黃連與吳茱萸配伍後,鹽痠小檗堿、鹽痠巴馬汀、鹽痠藥根堿的含量均顯著降低,以鹽痠小檗堿的減少較為明顯.結論:兩藥閤用,黃連生物堿含量均有不同程度降低,說明吳茱萸可製約黃連苦寒之性,為臨床兩藥配伍使用提供瞭實驗依據.
목적:비교황련중주요생물감성분재황련-오수유약대배오전후적차이.방법:채용TLCS법대황련단전액、황련오수유합전액、황련오수유단전혼합액중염산소벽감、염산파마정、염산약근감적함량진행측정.결과:황련여오수유배오후,염산소벽감、염산파마정、염산약근감적함량균현저강저,이염산소벽감적감소교위명현.결론:량약합용,황련생물감함량균유불동정도강저,설명오수유가제약황련고한지성,위림상량약배오사용제공료실험의거.
AIM: To investigate the changes of alkaloid in Rhizorrm Coptidis and Fructus Evodiae before and after combination. METHODS: The content of berberine hydrochloride,palmatine hydrochloride,jatrorrhizine hydrochloride in Rhizoma Coptidis and Fructus Evodiae before and after combination were determined by TLCS.RESULTS : After combination of Rhizoma Coptidis and Fructus Evodiae,contents of berberine hydrochioride,palmatine hydrochloride,jatrorrhizine hydrochloride significantly reduced,among which the reduction of berberine hydrochloride was more obvious.CONCLUSION: In decoction,Fructus Evodiae appears to restrict the alkaloid from Rhizoma Coptidis in order to lower the side effect of Rhizoma Coptidis.
