国际呼吸杂志
國際呼吸雜誌
국제호흡잡지
INTERNATIONAL JOURNAL OF RESPIRATION
2009年
5期
257-261
,共5页
阻塞性睡眠呼吸暂停低通气综合征%冠状动脉粥样硬化性心脏病%临床特征
阻塞性睡眠呼吸暫停低通氣綜閤徵%冠狀動脈粥樣硬化性心髒病%臨床特徵
조새성수면호흡잠정저통기종합정%관상동맥죽양경화성심장병%림상특정
Obstructive sleep apnea-hypopnea syndrome%Coronary artery disease%Clinical features
目的 了解冠状动脉粥样硬化性心脏病(coronary artery disease,CAD)患者中阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea-hypopnea syndrome,OSAHS)的患病率,并探讨其临床特征.方法 对2007年8月至2008年8月因胸痛、胸闷等类似心绞痛症状入住我院心脏中心行冠状动脉造影(coronary angiography,CAG)的患者进行多导睡眠图(polysomnography,PSG)监测,并分析CAD合并OSAHS患者的临床特征.结果 入选患者310例,合并OSAHS患者220例(70.97%).经CAG确诊CAD患者231例(74.52%),合并OSAHS患者168例(72.73%);CAG阴性患者79例,合并OSAHS患者52例(65.82%).CAD合并OSAHS患者与CAD不合并OSAHS患者之间颈围、腰臀比、夜间胸痛发作、嗜睡指数、夜间憋醒、夜尿增多、反酸、晨起口干、体质量指数均有显著差异.Logistic回归分析显示夜间胸痛、夜尿增多、晨起口干和肥胖是CAD合并OSAHS患者的重要危险因素.结论 以类似心绞痛症状就诊的患者中OSAHS的患病率高,尤其CAG阳性的患者;伴有夜间憋醒或胸痛、夜尿增多、晨起口干及肥胖的CAD患者要常规排查OSAHS.
目的 瞭解冠狀動脈粥樣硬化性心髒病(coronary artery disease,CAD)患者中阻塞性睡眠呼吸暫停低通氣綜閤徵(obstructive sleep apnea-hypopnea syndrome,OSAHS)的患病率,併探討其臨床特徵.方法 對2007年8月至2008年8月因胸痛、胸悶等類似心絞痛癥狀入住我院心髒中心行冠狀動脈造影(coronary angiography,CAG)的患者進行多導睡眠圖(polysomnography,PSG)鑑測,併分析CAD閤併OSAHS患者的臨床特徵.結果 入選患者310例,閤併OSAHS患者220例(70.97%).經CAG確診CAD患者231例(74.52%),閤併OSAHS患者168例(72.73%);CAG陰性患者79例,閤併OSAHS患者52例(65.82%).CAD閤併OSAHS患者與CAD不閤併OSAHS患者之間頸圍、腰臀比、夜間胸痛髮作、嗜睡指數、夜間憋醒、夜尿增多、反痠、晨起口榦、體質量指數均有顯著差異.Logistic迴歸分析顯示夜間胸痛、夜尿增多、晨起口榦和肥胖是CAD閤併OSAHS患者的重要危險因素.結論 以類似心絞痛癥狀就診的患者中OSAHS的患病率高,尤其CAG暘性的患者;伴有夜間憋醒或胸痛、夜尿增多、晨起口榦及肥胖的CAD患者要常規排查OSAHS.
목적 료해관상동맥죽양경화성심장병(coronary artery disease,CAD)환자중조새성수면호흡잠정저통기종합정(obstructive sleep apnea-hypopnea syndrome,OSAHS)적환병솔,병탐토기림상특정.방법 대2007년8월지2008년8월인흉통、흉민등유사심교통증상입주아원심장중심행관상동맥조영(coronary angiography,CAG)적환자진행다도수면도(polysomnography,PSG)감측,병분석CAD합병OSAHS환자적림상특정.결과 입선환자310례,합병OSAHS환자220례(70.97%).경CAG학진CAD환자231례(74.52%),합병OSAHS환자168례(72.73%);CAG음성환자79례,합병OSAHS환자52례(65.82%).CAD합병OSAHS환자여CAD불합병OSAHS환자지간경위、요둔비、야간흉통발작、기수지수、야간별성、야뇨증다、반산、신기구간、체질량지수균유현저차이.Logistic회귀분석현시야간흉통、야뇨증다、신기구간화비반시CAD합병OSAHS환자적중요위험인소.결론 이유사심교통증상취진적환자중OSAHS적환병솔고,우기CAG양성적환자;반유야간별성혹흉통、야뇨증다、신기구간급비반적CAD환자요상규배사OSAHS.
Objective To investgate the prevalence rate of obstructive sleep apnea-hypopnea syndrome (OSAHS) in patients with coronary artery disease(CAD) ,and to assess the clinical features of patients with OSAHS and CAD. Methods Polysomnography(PSG) monitoring was performed in all patients undergoing coronary angiography(CAG) from August 2007 to August 2008 in the Cardiovascular Disease Center of Beijing Chaoyang Hospital. The clinical features were recorded and analyzed. Results Angiography and PSG monitoring were performed in 310 consecutive inpatients. 231 patients were diagnosed as having CAD. There were 168 (72.73%) patients of the CAD patients who had OSAHS. Among the patients whose coronary angiography were negative, there were 52 (65.82%) patients who had OSAHS. There were significant differences of neck circumference, waist hip ratio, the frequences of nocturnal angina, nocturnal pilyuria, throat thirsty in the morning,and higher BMI between two groups. Logistic regression analysis showed that the frequences of nocturnal angina, nocturnal pilyuria, throat thristy in the morning and higher BMI were significant risk factors of the patients with CAD and OSAHS. Conclusions There is a high prevalence rate of OSAHS in patients with CAD,and PSG monitoring should be performed in patients with CAD,especially for patients with clinical features such as frequent nocturnal angina, nocturnal pilyuria, throat thirsty in the morning,and higher BMI.
