中华放射肿瘤学杂志
中華放射腫瘤學雜誌
중화방사종류학잡지
CHINESE JOURNAL OF RADIATION ONCOLOGY
2009年
4期
261-264
,共4页
陈俊强%潘建基%陈明强%朱坤寿%李云英%王捷忠%李建成%郑雄伟%吴君心%肖锦榕
陳俊彊%潘建基%陳明彊%硃坤壽%李雲英%王捷忠%李建成%鄭雄偉%吳君心%肖錦榕
진준강%반건기%진명강%주곤수%리운영%왕첩충%리건성%정웅위%오군심%초금용
食管肿瘤/外科学%食管肿瘤/放射疗法%预后
食管腫瘤/外科學%食管腫瘤/放射療法%預後
식관종류/외과학%식관종류/방사요법%예후
Esophageal neoplasmas/surgery%Esophageal neoplasmas/radiotherapy%Prognosis
目的 评价N0期食管鳞癌术后预防性放疗价值.方法 分析1993年1月至2006年12月我院收治的食管癌术后病理诊断证实鳞癌、无淋巴结转移及远处转移的N0期患者859例,其中单纯手术760例,术后放疗99例.术后3～4周开始放疗,放疗中位总剂量50 Gy,分25次,2 Gy/次,5次/周,5周完成.结果 5年生存率手术组和术后放疗组分别为72.2%和77.4%(x2=0.13,P>0.05).分层分析术后放疗较单纯手术可提高pT4期及病变长度>5cm的生存率,5年生存率分别为67.1%对34.6%(x2=7.72,P<0.05)和81.3%对70.2%(x2=4.01,P<0.05),并能降低pT4期瘤床复发率.结论 N0期食管鳞癌术后预防性放疗可明显提高pT4期及病变长度>5cm的生存率和降低pT4期瘤床复发率.
目的 評價N0期食管鱗癌術後預防性放療價值.方法 分析1993年1月至2006年12月我院收治的食管癌術後病理診斷證實鱗癌、無淋巴結轉移及遠處轉移的N0期患者859例,其中單純手術760例,術後放療99例.術後3～4週開始放療,放療中位總劑量50 Gy,分25次,2 Gy/次,5次/週,5週完成.結果 5年生存率手術組和術後放療組分彆為72.2%和77.4%(x2=0.13,P>0.05).分層分析術後放療較單純手術可提高pT4期及病變長度>5cm的生存率,5年生存率分彆為67.1%對34.6%(x2=7.72,P<0.05)和81.3%對70.2%(x2=4.01,P<0.05),併能降低pT4期瘤床複髮率.結論 N0期食管鱗癌術後預防性放療可明顯提高pT4期及病變長度>5cm的生存率和降低pT4期瘤床複髮率.
목적 평개N0기식관린암술후예방성방료개치.방법 분석1993년1월지2006년12월아원수치적식관암술후병리진단증실린암、무림파결전이급원처전이적N0기환자859례,기중단순수술760례,술후방료99례.술후3～4주개시방료,방료중위총제량50 Gy,분25차,2 Gy/차,5차/주,5주완성.결과 5년생존솔수술조화술후방료조분별위72.2%화77.4%(x2=0.13,P>0.05).분층분석술후방료교단순수술가제고pT4기급병변장도>5cm적생존솔,5년생존솔분별위67.1%대34.6%(x2=7.72,P<0.05)화81.3%대70.2%(x2=4.01,P<0.05),병능강저pT4기류상복발솔.결론 N0기식관린암술후예방성방료가명현제고pT4기급병변장도>5cm적생존솔화강저pT4기류상복발솔.
Objective To evaluate the value of postoperative prophylactic radiotherapy for N0 e-sophageal squamous carcinoma. Methods From January 1993 to December 2006,859 patients with patho-logically staged N0 and M0 esophageal squamous cell carcinoma were included in this study. Among them, 760 received surgery alone, and 99 received surgery followed by postoperative radiotherapy. Radiotherapy started within 3 to 4 weeks after surgery. The median total dose was 50 Gy(2 Gy/F,5 F/w). Results In surgery alone group and postoperative radiotherapy group,the 5-yeur overall survival rotes were 72.2% vs 77.4% (X2 =0. 13,P >0.05) for all patients,34.6% vs67.1% (X2 =7.72,P <0.05) forpT4 disease,and 70.2% vs 81.3% (X2 =4.01 ,P <0.05) for tumor length >5 cm. Postoperative radiotherapy could lower the recurrence rate for pT4 patients. Conclusions For patients with NO esophageal squamous carcinoma, postoperative radiotherapy can significantly improve the survival for pT4 and tumor length > 5 cm,and also re-duce the recurrence for pT4 patients.
