CAJ | 학술논문

目的评价灰阶谐波超声造影技术显示不同程度颈动脉狭窄患者动脉粥样硬化斑块内新生血管形成的价值.方法疑诊颈动脉狭窄患者58例,共73个斑块.常规超声评价颈动脉斑块回声类型,超声造影实时观察斑块内增强强度并进行分级.动脉狭窄程度以X线动脉造影检查结果为准.比较不同狭窄程度及不同回声类型颈动脉斑块的增强强度.结果颈动脉90%以下狭窄各组间斑块增强强度与动脉狭窄程度之间无相关性(P=0.358),但90%以上狭窄(包括闭塞)组斑块增强强度明显增加,两者之间差异有统计学意义(P=0.008).不同斑块回声类型的斑块增强强度差异有统计学意义(P=0.000).结论超声造影能够实时观察颈动脉粥样硬化斑块的增强过程,反映斑块内新生血管的形成,从而为评价斑块的稳定性提供重要信息.
목적 평개회계해파초성조영기술현시불동정도경동맥협착환자동맥죽양경화반괴내신생혈관형성적개치.방법 의진경동맥협착환자58례,공73개반괴.상규초성평개경동맥반괴회성류형,초성조영실시관찰반괴내증강강도병진행분급.동맥협착정도이X선동맥조영검사결과위준.비교불동협착정도급불동회성류형경동맥반괴적증강강도.결과 경동맥90%이하협착각조간반괴증강강도여동맥협착정도지간무상관성(P=0.358),단90%이상협착(포괄폐새)조반괴증강강도명현증가,량자지간차이유통계학의의(P=0.008).불동반괴회성류형적반괴증강강도차이유통계학의의(P=0.000).결론 초성조영능구실시관찰경동맥죽양경화반괴적증강과정,반영반괴내신생혈관적형성,종이위평개반괴적은정성제공중요신식.
Objective To evaluate contrast-enhanced ultrasound imaging of carotid atherosclerosis with different stenostic degree as a clinical tool to study intraplaque neovascularization.Methods Fifty-eight patients suspected of carotid stenosis with 73 plaques were studied by standard and contrast-enhanced ultrasound.Plaque echogenicity at standard ultrasound were evaluated.Contrast enhancement within the plaques was categorized as 0 - 4 degree and compared to the stenosis degree and the plaque echogenicity.The degree of stenosis was determined by intravenous digital subtraction angiography.Results In the group with stenosis less than 90% ,stenosis degree was not associated with the grade of contrast enhancement (P =0.358),while the grade of enhancement was significantly higher in the group with sever stenosis(＞90%).The grades of enhancement were significantly different between plaques with different echogenicity (P =0.000).Conclusions Contrast-enhanced real-time ultrasound imaging can demonstrate the enhancement of carotid plaques non-invasively,which is helpful for assessing intraplaque neovascularization and provide valuable information for plaque risk stratification