今日药学
今日藥學
금일약학
PHARMACY TODAY
2009年
7期
56-59
,共4页
排毒清脂胶囊%长期毒性
排毒清脂膠囊%長期毒性
배독청지효낭%장기독성
Paidu Qingzhi capsule%long-term toxicity
目的 研究排毒清脂胶囊对大鼠的长期毒性.方法 排毒清脂胶囊给药剂量分别为0.35、1.05、3.15 g/kg时,连续静脉滴注给药90 d.结果 对大鼠的行为、外观主要脏器心、肝、脾、肺、肾的重量比、肝脏和肾脏功能及血象均无明显影响.结论 该药长期服用较为安全,毒副作用不明显.
目的 研究排毒清脂膠囊對大鼠的長期毒性.方法 排毒清脂膠囊給藥劑量分彆為0.35、1.05、3.15 g/kg時,連續靜脈滴註給藥90 d.結果 對大鼠的行為、外觀主要髒器心、肝、脾、肺、腎的重量比、肝髒和腎髒功能及血象均無明顯影響.結論 該藥長期服用較為安全,毒副作用不明顯.
목적 연구배독청지효낭대대서적장기독성.방법 배독청지효낭급약제량분별위0.35、1.05、3.15 g/kg시,련속정맥적주급약90 d.결과 대대서적행위、외관주요장기심、간、비、폐、신적중량비、간장화신장공능급혈상균무명현영향.결론 해약장기복용교위안전,독부작용불명현.
Objective To study the long-term toxicity of Paidu Qingzhi capsule in rats. Methods Paidu Qingzhi capsule was administrated at 0.35, 1.05, 3.15 g/kg, ig, and was continual used for 90 d. Results The behavior and appearance of rats, the weight ratio of major organs (heart, liver, spleen, lung, kidney), the function and blood of liver and kidney was no significant change. Conclusion The long-term administration of Paidu Qingzhi capsule is safe, and has no side effects.
