CAJ | 학술논문

分析了经与黑曲霉基因组全序列杂交改造的轮梗霉融合株D-A1菌粉的一般营养成分及其对高脂小鼠血脂的调节作用和对动脉粥样硬化的预防.结果表明:菌粉含有15.21%的蛋白质和30.34%的粗脂肪,其中含有16.75%的花生四烯酸;以1.2g/kg菌粉饲喂小鼠35d,可有效预防血清总胆固醇(TC)、甘油三酯(TG)的升高,与高脂模型组相比,低密度脂蛋白-胆固醇(LDL-C)水甲降低了70.94%,而高密度脂蛋白-胆固醇(HDL-C)水甲提高了42.58%.轮梗霉融合株菌粉营养价值高,能有效的预防高脂血症,对小鼠脂代谢紊乱具有显著的调节作用.
분석료경여흑곡매기인조전서렬잡교개조적륜경매융합주D-A1균분적일반영양성분급기대고지소서혈지적조절작용화대동맥죽양경화적예방.결과표명:균분함유15.21%적단백질화30.34%적조지방,기중함유16.75%적화생사희산;이1.2g/kg균분사위소서35d,가유효예방혈청총담고순(TC)、감유삼지(TG)적승고,여고지모형조상비,저밀도지단백-담고순(LDL-C)수갑강저료70.94%,이고밀도지단백-담고순(HDL-C)수갑제고료42.58%.륜경매융합주균분영양개치고,능유효적예방고지혈증,대소서지대사문란구유현저적조절작용.
The dried mycelia ofDiasporangium sp. recombinant strain D-A1 which was a hybrid of Aspergillus niger and Diasporangium sp. obtained by genome shuffling was analyzed for their general nutritional ingredient and their regulation effect on blood lipids and prevention effect on atherosclerosis in mice were studied. The dried mycelia of the recombinant strain D-A1 contained 15.21% protein and 30.34% lipid of which arachidonic acid accounted for 16.75%. Obvious preventions in ascension of total cholesterol (TC) and triglyceride (TG) were found in high-fat model mice fed 1.2 g/kg of the dried mycelia of the recombinant swain D-A1 for 35 days. The low-density lipoprotein cholesterol (LDL-C) level of mycelia powder-fed group was reduced by 70.94% when compared with that of the high-fat diet model group, while the high-density lipoprotein cholesterol (HDL-C) level was found to be enhanced by 42.58%. The mycelia powder ofDiasporangium sp. recombinant strain D-A1 has a high nutritional value, which can prevent hyperlipemia effectively, and exhibits remarkable regulation actions to the blood lipid metabolism disorder of mice.