CAJ | 학술논문

目的评估颈内静脉氧饱和度(SjvO2)作为重型颅脑损伤的预后指标及与脑灌注压(CPP)的相关性. 方法回顾性分析2006年10月至2008年5月上海市闵行区中心医院收治的32例重型颅脑损伤患者,每6 h测定一次颈静脉搏氧饱和度,持续监测平均动脉压(MAP)及颅内压(ICP). 结果 SjvO2与重型颅脑损伤预后显著相关,SjvO2≤50%或SjvO2≥75%发作2次以上提示预后不良.在CPP＜70 mm Hg,SjvO2与CPP有显著的相关性,而CPP≥70 mm Hg组患者中,SjvO2与CPP无明显相关性. 结论 SjvO2与CPP监测相结合,能较可靠地反映脑供血及脑代谢状况,对重型颅脑损伤的治疗有指导意义.
목적 평고경내정맥양포화도(SjvO2)작위중형로뇌손상적예후지표급여뇌관주압(CPP)적상관성. 방법 회고성분석2006년10월지2008년5월상해시민행구중심의원수치적32례중형로뇌손상환자,매6 h측정일차경정맥박양포화도,지속감측평균동맥압(MAP)급로내압(ICP). 결과 SjvO2여중형로뇌손상예후현저상관,SjvO2≤50%혹SjvO2≥75%발작2차이상제시예후불량.재CPP＜70 mm Hg,SjvO2여CPP유현저적상관성,이CPP≥70 mm Hg조환자중,SjvO2여CPP무명현상관성. 결론 SjvO2여CPP감측상결합,능교가고지반영뇌공혈급뇌대사상황,대중형로뇌손상적치료유지도의의.
Objective To estimate the effects of jugular blood oxygen saturation (SjvO2) on prognosis of severe head injury and its relationship with cerebral perfusion pressure(CPP). Methods Thirty-two patients with severe head injury, in Minghang Central Hospital, Shanghai, between October 2006 and May 2008, were retrospectively analyzed. SjvO2 was detected every 6 hours. Continuous measurements of mean arterial pressure(MAP) and ICP were performed to assess the dependence of SjvO2 on the CPP. Results SjvO2 was significantly correlated with prognosis, SjvO2≤50% or ≥75% episodes two or more was associated with a poor neurology outcome. Changes of CPP induced highly significant alterations in SjvO2 in the patients with CPP＜70mm Hg. On the contrary, in the patients with CPP≥70 mm Hg, there was no correlation. Conclusions SjvO2 and CPP are reliable to predict prognosis of severe head injuries and helpful to treatment.