CAJ | 학술논문

采用静电纺技术制备聚酯酰胺纳米纤维膜,用扫描电镜观察纳米纤维的表面形貌,发现随着纺丝液质量浓度的增加,纤维的直径由10%时的180 nm递增到20%时的350 nm;用红外光谱表征聚酯酰胺的化学结构,结果表明化学结构在纺丝前后没有发生明显变化;X射线衍射法测试表明聚酯酰胺在经过溶剂处理和纺丝后,结晶度下降;差示扫描量热法表征了热力学特性,发现聚酯酰胺经过溶剂处理和纺丝后,结晶度下降;力学性能测试表明平均厚度为(0.50±0.05)mm的聚酯酰胺纳米纤维膜的平均断裂强度和平均断裂伸长率分别达到(1.00±0.18)MPa和(18.20±2.86)%;MTT结果表明内皮细胞在聚酯酰胺纳米纤维膜上增殖活跃,内皮细胞在纤维表面黏附并显示出良好的生长形态.
채용정전방기술제비취지선알납미섬유막,용소묘전경관찰납미섬유적표면형모,발현수착방사액질량농도적증가,섬유적직경유10%시적180 nm체증도20%시적350 nm;용홍외광보표정취지선알적화학결구,결과표명화학결구재방사전후몰유발생명현변화;X사선연사법측시표명취지선알재경과용제처리화방사후,결정도하강;차시소묘량열법표정료열역학특성,발현취지선알경과용제처리화방사후,결정도하강;역학성능측시표명평균후도위(0.50±0.05)mm적취지선알납미섬유막적평균단렬강도화평균단렬신장솔분별체도(1.00±0.18)MPa화(18.20±2.86)%;MTT결과표명내피세포재취지선알납미섬유막상증식활약,내피세포재섬유표면점부병현시출량호적생장형태.
The poly ester-amide (PEA) nanofiber membrane was prepared by electrospinning and the surface topography of nanofiber membrane was observed by scanning electron microscope (SEM). It was found that with the increasing of spinning fluid concentration from 10% to 20%, the diameter of prepared fibers was increased from 180 nm to 305 nm. The chemical structure of PEA was detected by infrared spectrum, which showed that electrospinning had no significant effect on PEA. X-ray diffraction spectrogram and differential scanning calorimetry revealed that the crystallinity of PEA was decreased after electrospinning. Mechanical property test demonstrated that the mean breaking strength and elongation at break of PEA nanofiber membrane with (0.50±0.05) mm thickness were (1.00±0.18) MPa, and (18.20±2.86)%, respectively. MTT results showed that the endothelial cells proliferated actively on the PEA nanofiber membrane, and presented good adhesive and growth status.