CAJ | 학술논문

研究了气升式生物反应器内红霉素发酵的动力学行为，根据所归纳出的动力学方程，调整发酵过程中的补料策略，得出了比较优化的工艺和工程参数，如发酵液的C/N(碳源/氮源)比、氧摄取速度(OUR)等。根据此动力学模型，调整的优化发酵工艺使得菌体代谢周期缩短了13％，而红霉素发酵水平提高了10%.
연구료기승식생물반응기내홍매소발효적동역학행위，근거소귀납출적동역학방정，조정발효과정중적보료책략，득출료비교우화적공예화공정삼수，여발효액적C/N(탄원/담원)비、양섭취속도(OUR)등。근거차동역학모형，조정적우화발효공예사득균체대사주기축단료13％，이홍매소발효수평제고료10%.
The kinetics of erythromycin fermentation in an air-lift bioreactor was studies.According to the kinetic equations,feeding strategies,the optimum process control parameters,the ratio of C/N(carbon/nitrogen)and oxygen uptake rates were obtained.It resulted in a significant improvement on the erythromycin fermentation.The total metabolic phase was reduced by 13% and the production was 10% higher than that by the traditional process.