CAJ | 학술논문

目的探讨糖尿病心肌病(DC)患者心率震荡(HRT)的变化及其临床意义.方法对DC患者33例及对照组30例进行24h动态心电图检查,分别计算震荡初始(TO)和震荡斜率(TS),比较两组患者TO及TS均值,并对TO、TS与24h正常窦性心律RR间期的标准差(SDNN)及左室舒张末内径(LEVDD)进行相关性分析.结果 DC组的TO值高于对照组[(-0.38±0.12)％与(-1.88±0.13)％；t=7.38,P=0.01],TS值低于对照组[(2.02±0.82)ms/R-R与(9.72±1.18)ms/R-R;t=18.69,P=0.02]；TO与SDNN及LEVDD有相关性(r=-0.35,P=0.02;r =0.68,P=0.01),TS亦与SDNN及LEVDD有相关性(r=0.45,P=0.01;r=-0.39,P=0.03).结论 DC患者HRT现象明显受损.
목적 탐토당뇨병심기병(DC)환자심솔진탕(HRT)적변화급기림상의의.방법 대DC환자33례급대조조30례진행24h동태심전도검사,분별계산진탕초시(TO)화진탕사솔(TS),비교량조환자TO급TS균치,병대TO、TS여24h정상두성심률RR간기적표준차(SDNN)급좌실서장말내경(LEVDD)진행상관성분석.결과 DC조적TO치고우대조조[(-0.38±0.12)％여(-1.88±0.13)％；t=7.38,P=0.01],TS치저우대조조[(2.02±0.82)ms/R-R여(9.72±1.18)ms/R-R;t=18.69,P=0.02]；TO여SDNN급LEVDD유상관성(r=-0.35,P=0.02;r =0.68,P=0.01),TS역여SDNN급LEVDD유상관성(r=0.45,P=0.01;r=-0.39,P=0.03).결론 DC환자HRT현상명현수손.
Objective To study the changes and clinical significance of heart rate turbulence(HRT)in patients with diabetic cardiomyopathy.Methods 24h Holter ECG recordings were examined in 33 patients with diabetic cardiomyopathy(DC)and 30 patients in the control group.Turbulence onset(TO)and turbulence slope (TS)were calculated from Holter recordings.The mean value of TO,TS between the two groups were compared,the relativity among TO,TS,SDNN and LEVDD were analyzed as well.Results TO was significantly higher in the DC group compared with the control group[(-0.38 ± 0.12)％ vs(-1.88 ± 0.13)％,t =7.38,P =0.01)].TS in the DC group was significantly lower than that in the control group[(2.02 ± 0.82)ms/R-R vs (9.72 ± 1.18)ms/R-R,t =18.69,P =0.02)].TO was significantly related to SDNN(r =-0.35,P =0.02)and LEVDD(r =0.68,P =0.01),TS was also significantly related to SDNN(r =0.45,P =0.01)and LEVDD (r =-0.39,P =0.03).Conclusion The manifest of heart rate turbulence is significantly impaired in patients with diabetic cardiomyopathy.