中华眼外伤职业眼病杂志
中華眼外傷職業眼病雜誌
중화안외상직업안병잡지
CHINESE JOURNAL OF OCULAR TRAUMA AND OCCUPATIONAL EYE DISEASE
2011年
10期
774-776
,共3页
角膜缘干细胞%移植%丝裂霉素C%翼状胬肉
角膜緣榦細胞%移植%絲裂黴素C%翼狀胬肉
각막연간세포%이식%사렬매소C%익상노육
Limbal stem cell%autografting%Mitomycin C%Pterygium
目的 观察自体角膜缘干细胞移植联合应用丝裂霉素C治疗原发性翼状胬肉的临床疗效.方法 自体角膜缘干细胞移植52例(52眼),其中联合丝裂霉素C应用26例(26眼),术后随访6个月～2年.结果 自体角膜缘干细胞移植组角膜上皮愈合快,刺激症状较轻,角膜上皮愈合时间(3～5)d.联合丝裂霉素C组角膜上皮愈合较慢,刺激症状重且持续时间较长,角膜上皮愈合时间(5～9)d.自体角膜缘干细胞移植组与联合丝裂霉素C组各有1例复发,复发率均为3.85％.联合丝裂霉素C组有2例结膜移植片融解.结论 两组复发率均较低.掌握丝裂霉素C的适应证,警惕其并发症.
目的 觀察自體角膜緣榦細胞移植聯閤應用絲裂黴素C治療原髮性翼狀胬肉的臨床療效.方法 自體角膜緣榦細胞移植52例(52眼),其中聯閤絲裂黴素C應用26例(26眼),術後隨訪6箇月～2年.結果 自體角膜緣榦細胞移植組角膜上皮愈閤快,刺激癥狀較輕,角膜上皮愈閤時間(3～5)d.聯閤絲裂黴素C組角膜上皮愈閤較慢,刺激癥狀重且持續時間較長,角膜上皮愈閤時間(5～9)d.自體角膜緣榦細胞移植組與聯閤絲裂黴素C組各有1例複髮,複髮率均為3.85％.聯閤絲裂黴素C組有2例結膜移植片融解.結論 兩組複髮率均較低.掌握絲裂黴素C的適應證,警惕其併髮癥.
목적 관찰자체각막연간세포이식연합응용사렬매소C치료원발성익상노육적림상료효.방법 자체각막연간세포이식52례(52안),기중연합사렬매소C응용26례(26안),술후수방6개월～2년.결과 자체각막연간세포이식조각막상피유합쾌,자격증상교경,각막상피유합시간(3～5)d.연합사렬매소C조각막상피유합교만,자격증상중차지속시간교장,각막상피유합시간(5～9)d.자체각막연간세포이식조여연합사렬매소C조각유1례복발,복발솔균위3.85％.연합사렬매소C조유2례결막이식편융해.결론 량조복발솔균교저.장악사렬매소C적괄응증,경척기병발증.
Objective To evaluate the effficacy of limbal stem cell autografting combined with mitomycin C for treatment of pterygium.Methods 52 cases were divided into 2 groups,with 26 in each group.One group received autologous limbal stem cells autografting,the other group received the same operation with mitomycin C.The cases were followed up for 6 months to 2 years.Results Corneal epithelia of limbal stem cells autografting group recovered quickly and postoperative response was slight.The recovering time of corneal epithelia was (3 + 0.5 ) d.Comesl epithelia of group with mitomycin C recovered slowly,irritating response was strong and lasted for a long time.The recovering time of cornesl epithelia was (7 ± 0.5 ) d.One case reoccurred in each group and the reoccurrance rate was 3.8％.Two cases had melt conjunctival grafts in mitomycin C group.Conclusions Two groups have low recurrence rate.We should know the indication for application of mitomycin C and pay more attention to its complications.
