CAJ | 학술논문

目的探讨幽门螺杆菌(Hp)感染与缺铁性贫血(IDA)的关系,以及Hp相关IDA的治疗.方法分别统计40例IDA伴慢性胃炎与42例非IDA慢性胃炎两组Hp感染率.将36例Hp感染相关IDA随机分成两组,分别应用根除细菌加口服铁剂与单用铁剂方案治疗,检测治疗前后血液学指标,观察疗效.结果 IDA伴慢性胃炎者Hp感染率为90%高于非IDA慢性胃炎者(70%),两者差异有统计学意义;Hp感染相关IDA患者接受根除细菌加铁剂治疗前后其Hb、血清铁、铁蛋白均显著增高,而单用铁剂组治疗前后血液学指标无显著变化.结论 Hp感染与IDA可能有一定相关性,当IDA患者铁剂治疗效果不显著时宜考虑是否存在Hp相关IDA;根除Hp感染后对IDA有一定治疗作用.
목적 탐토유문라간균(Hp)감염여결철성빈혈(IDA)적관계,이급Hp상관IDA적치료.방법 분별통계40례IDA반만성위염여42례비IDA만성위염량조Hp감염솔.장36례Hp감염상관IDA수궤분성량조,분별응용근제세균가구복철제여단용철제방안치료,검측치료전후혈액학지표,관찰료효.결과 IDA반만성위염자Hp감염솔위90%고우비IDA만성위염자(70%),량자차이유통계학의의;Hp감염상관IDA환자접수근제세균가철제치료전후기Hb、혈청철、철단백균현저증고,이단용철제조치료전후혈액학지표무현저변화.결론 Hp감염여IDA가능유일정상관성,당IDA환자철제치료효과불현저시의고필시부존재Hp상관IDA;근제Hp감염후대IDA유일정치료작용.
Objective To investigate the relationship between infection of helicobaeter pylori(Hp) and iron deficiency anemia(IDA) and to explore effective clinical treatments for patients with Hp associated IDA . Method 1. The Hp infection ratio of 40 chronic gastritis with IDA and 42 patients without IDA were counted up respectively. 2. 36 patients with Hp-positive chronic gastritis were divided into two groups randomly. One group was treated by using Hp eradication therapy in conjunction with oral iron supplement and the other using iron supplement only. The hema-tological parameters before and after treatment are measured and the effectiveness of the treatment was evaluated. Re-sult The Hp infection ratio in chronic gastritis patients with IDA is |figher than that in patients without IDA and the difference is significant. After Hp eradication therapy in conjunction with iron supplement Hb. serum iron and serum ferritin level in Hp associated IDA patients are increased significantly while that for patients treated by using iron sup-plement only have no significant improvement. Conclusion It appears that Hp infection may be related to IDA. When iron supplement treatment has no obvious effect to an IDA patient,lt may suggest a ease of Hp associated IDA. The i-ton supplement treatment has positive effects to IDA patients after Hp eradication.