CAJ | 학술논문

目的研究腰椎间盘髓核T2信号强度与患者年龄、性别及与髓核退变程度的关系.方法回顾性分析422例腰椎间盘退行性变患者的MRI资料,在正中矢状位上测量髓核T2wI信号强度值.对不同级别的信号值进行非参数相关分析和t检验；对年龄与椎间盘信号值及退变级别采用卡方检验和相关分析；对不同椎间盘水平的信号值进行t检验；对不同椎间盘水平间信号值进行非参数Spearman相关性分析.结果不同性别在同一级别和同一椎间盘水平的信号值差异均有统计学意义；年龄越大髓核信号值越低,髓核退变程度越高.T2WI信号强度可以代表椎间盘髓核退变程度.在所有腰椎间盘中第4～5腰椎间盘退变发生率最高.结论腰椎间盘髓核T2信号强度与髓核退变程度及患者年龄具有相关性.T2信号强度有可能成为一种评价髓核退变简便、易行的方法.
목적 연구요추간반수핵T2신호강도여환자년령、성별급여수핵퇴변정도적관계.방법 회고성분석422례요추간반퇴행성변환자적MRI자료,재정중시상위상측량수핵T2wI신호강도치.대불동급별적신호치진행비삼수상관분석화t검험；대년령여추간반신호치급퇴변급별채용잡방검험화상관분석；대불동추간반수평적신호치진행t검험；대불동추간반수평간신호치진행비삼수Spearman상관성분석.결과 불동성별재동일급별화동일추간반수평적신호치차이균유통계학의의；년령월대수핵신호치월저,수핵퇴변정도월고.T2WI신호강도가이대표추간반수핵퇴변정도.재소유요추간반중제4～5요추간반퇴변발생솔최고.결론 요추간반수핵T2신호강도여수핵퇴변정도급환자년령구유상관성.T2신호강도유가능성위일충평개수핵퇴변간편、역행적방법.
Objective To investigate the relation between T2 signal intensity in nucleus pulposus of lumbar discs with patient age,gender and stage of nucleus pulposus degeneration.Methods Lumbar imaging findings of 422 cases subjects were retrospectively reviewed through T2 signal intensity of nucleus pulposus evaluated based on the signal intensity of MR T2 - weighted mid - sagittal images of the lumbar spine,The T2 signal intensity at all five lumbar levels ( from L5 - S1 to L1 - L2 ) between male and female was used independent sample t -test and the Spearman correlation analysis.The age and grade of nucleus pulposus of disc degeneration and T2 signal intensity were estimated by calculating and Chi - square test and the Spearman correlation analysis ; The t - test was used to correlate the different anatomic levels of disc degeneration; T2 signal intensity among the five different anatomic levels using non -parametric correlation analysis.Results There were significant differences in T2 signal intensity of nucleus pulposus at the same grade and anatomic level between male and female.Advanced with age,T2 signal intensity of nucleus pulposus will decrease and stage of disc degeneration increasing accordingly.T2 signal intensity may represent the nucleus pulposus degeneration of interverterbral disc.L4 - L5 was the highest incidence among the nucleus pulposus degeneration of intervertebral disc.Conclusions T2 signal intensity of nucleus pulposus of lumbar interverterbral disc is correlated with grade of degeneration and patient age.The T2 signal intensity based approach may be a feasible and practical tool to determine nucleus pulposus degeneration.