肿瘤研究与临床
腫瘤研究與臨床
종류연구여림상
CANCER RESEARCH AND CLINIC
2011年
7期
447-449
,共3页
胃癌%HDL-C%淋巴结转移
胃癌%HDL-C%淋巴結轉移
위암%HDL-C%림파결전이
Gastric carcinoma%HDL-C%Lymphatic metastasis
目的 观察胃癌患者血清高密度脂蛋白(HDL-C)、低密度脂蛋白(LDL-C)水平与肿瘤临床分期、淋巴结转移的关系.方法 结合临床资料,回顾性分析2002年1月至2006年12月间收治的经病理学确诊的114例胃癌患者血清HDL-C、LDL-c的含量与临床病理特征之间的关系.结果 血清HDL-C水平和胃癌分化程度、淋巴结转移及肿瘤的大小有密切关系(P=0.015,P=0.023,P=0.006),TNMⅢ、Ⅳ期胃癌患者血清HDL-C水平明显低于Ⅰ、Ⅱ期患者(P=0.004,P=0.001).结论 术前测定患者血清HDL-C水平可能是预测胃癌淋巴结转移及判断胃癌病情进程的一个指标.
目的 觀察胃癌患者血清高密度脂蛋白(HDL-C)、低密度脂蛋白(LDL-C)水平與腫瘤臨床分期、淋巴結轉移的關繫.方法 結閤臨床資料,迴顧性分析2002年1月至2006年12月間收治的經病理學確診的114例胃癌患者血清HDL-C、LDL-c的含量與臨床病理特徵之間的關繫.結果 血清HDL-C水平和胃癌分化程度、淋巴結轉移及腫瘤的大小有密切關繫(P=0.015,P=0.023,P=0.006),TNMⅢ、Ⅳ期胃癌患者血清HDL-C水平明顯低于Ⅰ、Ⅱ期患者(P=0.004,P=0.001).結論 術前測定患者血清HDL-C水平可能是預測胃癌淋巴結轉移及判斷胃癌病情進程的一箇指標.
목적 관찰위암환자혈청고밀도지단백(HDL-C)、저밀도지단백(LDL-C)수평여종류림상분기、림파결전이적관계.방법 결합림상자료,회고성분석2002년1월지2006년12월간수치적경병이학학진적114례위암환자혈청HDL-C、LDL-c적함량여림상병리특정지간적관계.결과 혈청HDL-C수평화위암분화정도、림파결전이급종류적대소유밀절관계(P=0.015,P=0.023,P=0.006),TNMⅢ、Ⅳ기위암환자혈청HDL-C수평명현저우Ⅰ、Ⅱ기환자(P=0.004,P=0.001).결론 술전측정환자혈청HDL-C수평가능시예측위암림파결전이급판단위암병정진정적일개지표.
Objective To investigate the correlation of serum levels of HDL-C,LDL-C with clinical stage and lynlphatic metastasis in gastric malignant tumors. Methods Preoperative serum levels of HDL-C and LDL-C were retrospectively analyzed in 114 gastric cancer patients who were diagnosed by pathology.Results Serum, levels of HDL-C showed a remarkable correlation with tumor differentiation,lymphatic metastasis and the diameter of tumor in gastric cancer (P＜0.05).The lower serum levels of HDL-C were significantly observed in gastric cancer patients with TNM Ⅲ and IV stage,compared with those with TNM Ⅰ and Ⅱ stage (P＜0.05). Conclusion Preoperative serum levels of HDL-C might be a useful biomarker of lymphatic metastasis and advanced stage of gastric cancer.
