CAJ | 학술논문

目的分析总结医院骨伤和烧伤患者开放性伤口病原菌的分布及耐药状况.方法用VITEK-AMS微生物自动分析仪鉴定菌种和药物试验,对菌种分布特点及耐药性进行分析,同时对大肠埃希菌和肺炎克雷伯菌进行ESBLs检测.结果开放性伤口感染病原菌分离率最高的为铜绿假单胞菌(18.9%),其后依次为大肠埃希菌(13.3%)、凝固酶阴性葡萄球菌(10.1%)、金黄色葡萄球菌(9.5%)、克雷伯菌属(7.2%)和真菌(6.9%)等;大肠埃希菌和肺炎克雷伯菌ESBLs检出率分别为32.5%和6.5%;铜绿假单胞菌对常用抗菌药物已有较高耐药性;大肠埃希菌和肺炎克雷伯菌对亚胺培南100%敏感.结论了解开放性伤口感染病原菌的组成结构及其耐药变化趋势,可加强抗感染治疗的针对性和主动性,为临床取得最佳的感染防治效果提供科学依据.
목적 분석총결의원골상화소상환자개방성상구병원균적분포급내약상황.방법 용VITEK-AMS미생물자동분석의감정균충화약물시험,대균충분포특점급내약성진행분석,동시대대장애희균화폐염극뢰백균진행ESBLs검측.결과 개방성상구감염병원균분리솔최고적위동록가단포균(18.9%),기후의차위대장애희균(13.3%)、응고매음성포도구균(10.1%)、금황색포도구균(9.5%)、극뢰백균속(7.2%)화진균(6.9%)등;대장애희균화폐염극뢰백균ESBLs검출솔분별위32.5%화6.5%;동록가단포균대상용항균약물이유교고내약성;대장애희균화폐염극뢰백균대아알배남100%민감.결론 료해개방성상구감염병원균적조성결구급기내약변화추세,가가강항감염치료적침대성화주동성,위림상취득최가적감염방치효과제공과학의거.
Objective To study the distribution of pathogenic bacteria and their drug resistance during open wound infection in patients with bone trauma and burn injury in the past four years.Methods VITEK-AMS Automatic Microbial Analyzer was employed to identify the species and perform drug susceptibility test,and then the pathogenic bacteria distributed characteristic and drug resistance were analyzed. Meanwhile,ESBLs produced by E. coli and K. pneumoniae were detected.Results The isolated rate of Pseudomonas aeruginosa was the highest (18.9%) in open wound infection,followed by that of E. coli (13.3%),coagulase negative staphylococcus (10.1%),Staphylococcus aureus (9.5%),K. pneumoniae (7.2%),and fungi (6.9%). The detection rate of ESBLs was 32.5% and 6.5% for E. coli and K. respectively. Pseudomonas aeruginosa was high resistant to commly-used antibiotics. E. coli and K. pneumoniae were 100% sensitive to imipenem.Conclusion Understanding of the pathogenic bacteria distribution and drug resistance tendency contributes to the enhancement of antibiotical therapy specificity and activity,and providing scientific basis for optimal efficiency of prevention and treantment for infection.