CAJ | 학술논문

从变绿红菇子实体中提取出4种多糖,检测了它们的化学组成和分子量,并通过体内和体外实验,检测其抗肿瘤活性.结果表明,变绿红菇子实体的4种多糖为杂多塘,含有的单糖组分分别为木糖、葡萄糖、半乳糖、甘露糖以及果糖,其中葡萄糖为主要单糖组分.这4种多糖的重均分子量分别为3.1×107,6.5×105,5.1×105,8.0×105Da;多糖RVP2有较好的抗肿瘤活性,此发现为变绿红菇的深入开发利用提供了有价值的依据.
종변록홍고자실체중제취출4충다당,검측료타문적화학조성화분자량,병통과체내화체외실험,검측기항종류활성.결과표명,변록홍고자실체적4충다당위잡다당,함유적단당조분분별위목당、포도당、반유당、감로당이급과당,기중포도당위주요단당조분.저4충다당적중균분자량분별위3.1×107,6.5×105,5.1×105,8.0×105Da;다당RVP2유교호적항종류활성,차발현위변록홍고적심입개발이용제공료유개치적의거.
Four water-soluble polysaccharides were sequentially extracted from the fresh fruiting bodies of Russula virescens, and their chemical and physical characteristics were determined. The antitumor activities against Sarcoma 180 tumor cell (S-180) were then tested both in vitro and in vivo. The heteropolysaccharides consisted of xylose, mannese, glucose, galactose, and fructose. The weight average molecular weights (MWs) of polysaccharides RVP1, RVP2, RVP3, and RVP4 were determined to be 3.1×107,6.5×105,5.1×105, and 8.0×105Da, respectively. Except for RVP2, the other three polysaccharides were ineffective in suppressing S-180 growth. This find can the utilization of Russula virescens.