CAJ | 학술논문

目的探讨血管内径追踪和矢量应变技术在评价颈总动脉血管弹性中的价值.方法病例组选择单纯糖尿病患者38例,与病例组年龄、性别匹配的健康志愿者37例作为对照组.应用血管内径追踪和矢量应变技术测量颈总动脉弹性指标:脉搏波传导速度(PWV)、顺应性系数(CC)、僵硬指数(β),内膜环向应变、应变率、应变时间,外膜环向应变、应变率、应变时间,径向应变、应变率、应变时间.分析两组间参数的显著性差异及相关性.结果糖尿病组颈总动脉PWV、β较对照组显著增高(P＜0.05),CC较对照组明显减低(P＜0.05)；内外膜环向应变、应变率和径向应变、应变率指标较对照组显著减低(P＜0.05),相对应的应变时间较对照组延长(P＜0.05)；两组间纵向应变指标差异无统计学意义.糖尿病组CC与PWV呈显著负相关(r=-0.872,P＜0.001),年龄、收缩压、β与PWV正相关(分别r=0.322,P=0.005；r=0.384,P=0.001; r =0.927,P＜0.001).结论血管内径追踪技术所测量的硬度及顺应性指标和矢量应变技术所获得的环向及径向应变指标能够直观地反映糖尿病患者血管弹性的变化.
목적 탐토혈관내경추종화시량응변기술재평개경총동맥혈관탄성중적개치.방법 병례조선택단순당뇨병환자38례,여병례조년령、성별필배적건강지원자37례작위대조조.응용혈관내경추종화시량응변기술측량경총동맥탄성지표:맥박파전도속도(PWV)、순응성계수(CC)、강경지수(β),내막배향응변、응변솔、응변시간,외막배향응변、응변솔、응변시간,경향응변、응변솔、응변시간.분석량조간삼수적현저성차이급상관성.결과 당뇨병조경총동맥PWV、β교대조조현저증고(P＜0.05),CC교대조조명현감저(P＜0.05)；내외막배향응변、응변솔화경향응변、응변솔지표교대조조현저감저(P＜0.05),상대응적응변시간교대조조연장(P＜0.05)；량조간종향응변지표차이무통계학의의.당뇨병조CC여PWV정현저부상관(r=-0.872,P＜0.001),년령、수축압、β여PWV정상관(분별r=0.322,P=0.005；r=0.384,P=0.001; r =0.927,P＜0.001).결론 혈관내경추종기술소측량적경도급순응성지표화시량응변기술소획득적배향급경향응변지표능구직관지반영당뇨병환자혈관탄성적변화.
Objective To investigate the clinical value of blood vessel diameter tracking and X-strain technology in evaluating the carotid elasticity in patients with diabetes.Methods Thirty-eight patients who were confirmed as diabetes without complications were enrolled in this study as the patient group and thirtyseven healthy volunteers matched with the patient group with sex,ages were typed as controls.The parameters reflecting common carotid elasticity:pulse wave velocity ( PWV),compliance coefficient (CC),stiffness index ( β),endovascular circumferential strain,strain rate,strain time ( EN _ CS,EN _ CS_ T,EN_CSR,EN_CSR_T),adventitial circumferential strain,strain rate,strain time (EP_CS,EP_CS_T,EP_CSR,EP_ CSR_ T),radial strain ( RS),radial strain rate (RSR) and radial strain time (RST) were measured using blood vessel diameter tracking technique and X-strain technique.Significant difference between the two groups and correlations among these variables were evaluated.Results In patient group,PWV and β were significantly higher than those of the control group,while variables like CC,EN_CS,EN_CSR,EP_CS,EP_CSR,RS and RSR were lower with P ＜0.05.All strain time prolonged in patient group ( P ＜0.05).No significant differences were observed in longitudinal strain index.Furthermore,CC was inversely related with PWV( r =- 0.872,P ＜0.001 ),and age,systolic pressure,β were positively related with PWV ( r =0.322,P =0.005; r =0.384,P =0.001; r =0.927,P ＜0.001) in patients group.Conclusions The stiffness and compliance indexes measured by blood vessel diameter tracking technique and the circumferential and radial strain index obtained by X-strain technique can reflect vessel elasticity change of patient with diabetes objectively.