CAJ | 학술논문

目的探讨脑卒中后偏瘫侧下肢运动功能恢复的机制.方法通过血氧水平依赖性功能磁共振成像(BOLD-fMRI)技术研究7例脑卒中患者屈伸偏瘫侧膝关节时脑激活情况并与8例健康志愿者屈伸单侧膝关节时脑激活情况进行比较,用SPM5图像处理软件处理功能磁共振成像(fMRI)资料.结果 8例正常志愿者实际屈伸单侧膝关节时,对侧旁中央小叶、对侧辅助运动区.Brodmann 6区(BA6)、右侧颞上回及两侧顶下小叶明显激活.7例脑卒中患者中有6例屈伸偏瘫侧膝关节时脑激活区主要位于健侧半球顶叶BA7、BA5等脑区.结论健侧半球的代偿激活是脑卒中偏瘫下肢运动功能恢复的一个主要机制,脑卒中后偏瘫侧膝关节屈伸可能直接依赖于健侧半球顶叶BA7、BA5的激活.
목적 탐토뇌졸중후편탄측하지운동공능회복적궤제.방법 통과혈양수평의뢰성공능자공진성상(BOLD-fMRI)기술연구7례뇌졸중환자굴신편탄측슬관절시뇌격활정황병여8례건강지원자굴신단측슬관절시뇌격활정황진행비교,용SPM5도상처리연건처리공능자공진성상(fMRI)자료.결과 8례정상지원자실제굴신단측슬관절시,대측방중앙소협、대측보조운동구.Brodmann 6구(BA6)、우측섭상회급량측정하소협명현격활.7례뇌졸중환자중유6례굴신편탄측슬관절시뇌격활구주요위우건측반구정협BA7、BA5등뇌구.결론 건측반구적대상격활시뇌졸중편탄하지운동공능회복적일개주요궤제,뇌졸중후편탄측슬관절굴신가능직접의뢰우건측반구정협BA7、BA5적격활.
Objective To investigate the underlying mechanism of motor recovery of the hemiplegic lower extremity in stroke patients. Methods The brain activation pattern during sequential extension-flexion of the affect-ed knee of 7 stroke patients and 8 healthy subjects was observed by blood-oxygen- level-dependent fMRI (BOLD-fM-RI) and analyzed by microsoft SPM5. Results When executing unilateral knee flexion-extension, contralateral paracentral lobe and contralateral supplementary motor area and right temporal gyms and inferior parietal lobes of both sides were significantly activated in all the healthy subjects, while the ipsilateral parietal lobe BA7 and BA5 were sig-nificantly activated in 6 of the 7 stroke patients. Conclusions Sequential extension-flexion of the affected knee of stroke patients was probably dependent on the activation of BA7 and BA5 in the intact side. Compensatory activation of the intact hemisphere might be one of the main mechanisms for the paretic lower extremity motor recovery in stroke patients.