中华物理医学与康复杂志
中華物理醫學與康複雜誌
중화물리의학여강복잡지
CHINESE JOURNAL OF PHYSICAL MEDICINE AND REHABILITATION
2008年
11期
756-759
,共4页
吴军发%吴毅%胡永善%姜鹭春%刘树永%刘含秋
吳軍髮%吳毅%鬍永善%薑鷺春%劉樹永%劉含鞦
오군발%오의%호영선%강로춘%류수영%류함추
脑卒中%膝关节屈伸%功能磁共振成像
腦卒中%膝關節屈伸%功能磁共振成像
뇌졸중%슬관절굴신%공능자공진성상
Stroke%Knee flexion-extension%Functional magnetic resonance imaging
目的 探讨脑卒中后偏瘫侧下肢运动功能恢复的机制.方法 通过血氧水平依赖性功能磁共振成像(BOLD-fMRI)技术研究7例脑卒中患者屈伸偏瘫侧膝关节时脑激活情况并与8例健康志愿者屈伸单侧膝关节时脑激活情况进行比较,用SPM5图像处理软件处理功能磁共振成像(fMRI)资料.结果 8例正常志愿者实际屈伸单侧膝关节时,对侧旁中央小叶、对侧辅助运动区.Brodmann 6区(BA6)、右侧颞上回及两侧顶下小叶明显激活.7例脑卒中患者中有6例屈伸偏瘫侧膝关节时脑激活区主要位于健侧半球顶叶BA7、BA5等脑区.结论 健侧半球的代偿激活是脑卒中偏瘫下肢运动功能恢复的一个主要机制,脑卒中后偏瘫侧膝关节屈伸可能直接依赖于健侧半球顶叶BA7、BA5的激活.
目的 探討腦卒中後偏癱側下肢運動功能恢複的機製.方法 通過血氧水平依賴性功能磁共振成像(BOLD-fMRI)技術研究7例腦卒中患者屈伸偏癱側膝關節時腦激活情況併與8例健康誌願者屈伸單側膝關節時腦激活情況進行比較,用SPM5圖像處理軟件處理功能磁共振成像(fMRI)資料.結果 8例正常誌願者實際屈伸單側膝關節時,對側徬中央小葉、對側輔助運動區.Brodmann 6區(BA6)、右側顳上迴及兩側頂下小葉明顯激活.7例腦卒中患者中有6例屈伸偏癱側膝關節時腦激活區主要位于健側半毬頂葉BA7、BA5等腦區.結論 健側半毬的代償激活是腦卒中偏癱下肢運動功能恢複的一箇主要機製,腦卒中後偏癱側膝關節屈伸可能直接依賴于健側半毬頂葉BA7、BA5的激活.
목적 탐토뇌졸중후편탄측하지운동공능회복적궤제.방법 통과혈양수평의뢰성공능자공진성상(BOLD-fMRI)기술연구7례뇌졸중환자굴신편탄측슬관절시뇌격활정황병여8례건강지원자굴신단측슬관절시뇌격활정황진행비교,용SPM5도상처리연건처리공능자공진성상(fMRI)자료.결과 8례정상지원자실제굴신단측슬관절시,대측방중앙소협、대측보조운동구.Brodmann 6구(BA6)、우측섭상회급량측정하소협명현격활.7례뇌졸중환자중유6례굴신편탄측슬관절시뇌격활구주요위우건측반구정협BA7、BA5등뇌구.결론 건측반구적대상격활시뇌졸중편탄하지운동공능회복적일개주요궤제,뇌졸중후편탄측슬관절굴신가능직접의뢰우건측반구정협BA7、BA5적격활.
Objective To investigate the underlying mechanism of motor recovery of the hemiplegic lower extremity in stroke patients. Methods The brain activation pattern during sequential extension-flexion of the affect-ed knee of 7 stroke patients and 8 healthy subjects was observed by blood-oxygen- level-dependent fMRI (BOLD-fM-RI) and analyzed by microsoft SPM5. Results When executing unilateral knee flexion-extension, contralateral paracentral lobe and contralateral supplementary motor area and right temporal gyms and inferior parietal lobes of both sides were significantly activated in all the healthy subjects, while the ipsilateral parietal lobe BA7 and BA5 were sig-nificantly activated in 6 of the 7 stroke patients. Conclusions Sequential extension-flexion of the affected knee of stroke patients was probably dependent on the activation of BA7 and BA5 in the intact side. Compensatory activation of the intact hemisphere might be one of the main mechanisms for the paretic lower extremity motor recovery in stroke patients.