实用口腔医学杂志
實用口腔醫學雜誌
실용구강의학잡지
JOURNAL OF PRACTICAL STOMATOLOGY
2010年
1期
100-102
,共3页
口腔鳞状细胞癌%细胞角蛋白19片段%肿瘤标志物
口腔鱗狀細胞癌%細胞角蛋白19片段%腫瘤標誌物
구강린상세포암%세포각단백19편단%종류표지물
Oral squamous cell carcinoma%Cytokeratin 19 fragment%Tumor marker
目的:探讨口腔鳞癌患者血清Cyfra21-1的含量及潜在的临床应用价值.方法:采用ELISA技术检测31 例口腔鳞癌患者和28 例正常健康人血清中Cyfra21-1含量.结果:口腔鳞癌组血清Cyfra21-1含量为(1.12±0.61) ng/ml,高于正常组(0.34±0.20) ng/ml和良性肿瘤组(0.50±0.27) ng/ml(P<0.01);检测的敏感度、特异度分别为83.9%和89.3%;10 例口腔鳞癌患者血清Cyfra21-1含量由术前的(1.31±0.25) ng/ml降至术后的 (0.65±0.14) ng/ml,差异具显著性(P<0.01).结论:血清Cyfra21-1含量可作为口腔鳞癌的辅助诊断指标.
目的:探討口腔鱗癌患者血清Cyfra21-1的含量及潛在的臨床應用價值.方法:採用ELISA技術檢測31 例口腔鱗癌患者和28 例正常健康人血清中Cyfra21-1含量.結果:口腔鱗癌組血清Cyfra21-1含量為(1.12±0.61) ng/ml,高于正常組(0.34±0.20) ng/ml和良性腫瘤組(0.50±0.27) ng/ml(P<0.01);檢測的敏感度、特異度分彆為83.9%和89.3%;10 例口腔鱗癌患者血清Cyfra21-1含量由術前的(1.31±0.25) ng/ml降至術後的 (0.65±0.14) ng/ml,差異具顯著性(P<0.01).結論:血清Cyfra21-1含量可作為口腔鱗癌的輔助診斷指標.
목적:탐토구강린암환자혈청Cyfra21-1적함량급잠재적림상응용개치.방법:채용ELISA기술검측31 례구강린암환자화28 례정상건강인혈청중Cyfra21-1함량.결과:구강린암조혈청Cyfra21-1함량위(1.12±0.61) ng/ml,고우정상조(0.34±0.20) ng/ml화량성종류조(0.50±0.27) ng/ml(P<0.01);검측적민감도、특이도분별위83.9%화89.3%;10 례구강린암환자혈청Cyfra21-1함량유술전적(1.31±0.25) ng/ml강지술후적 (0.65±0.14) ng/ml,차이구현저성(P<0.01).결론:혈청Cyfra21-1함량가작위구강린암적보조진단지표.
Objective: To examine the level of serum Cyfra21-1 in patients with oral squamous cell carcinoma(OSCC) and to explore the potential application of serum Cyfra21-1 detection in the diagnosis of OSCC. Methods: The serum Cyfra21-1 concentrations were detected by ELISA. Results: The preoperative serum Cyfra21-1 concentration in patients with OSCC was (1.12±0.61) ng/ml, which was significantly higher than that in healthy persons (0.34±0.20) ng/ml and that in patients with oral benign tumor (0.50±0.27) ng/ml. The sensitivity rate and specificity rate of the test were 83.9% and 89.3%, respectively. For 10 patients with OSCC, the serum Cyfra21-1 concentrations were decreased from (1.31±0.25) ng/ml preoperatively to (0.65±0.14) ng/ml postoperatively. Conclusion: Cyfra21-1 may be a good marker in diagnosis of OSCC.
